Trabecular Network
Trabecular Network - Related Videos
09:03
Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
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Cited by 7 •
2015
Trabecular meshwork (TM) migration into Schlemm’s canal space can be induced by acute pressure elevation by ophthalmodynamometer, and observed by spectral domain optical coherence tomography. The goal of this method is to quantify the morphometric response of the living outflow tract to acute pressure elevation in living tissues in situ.
02:26
Protein Networks
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2020
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions. These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
02:18
Network Covalent Solids
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2020
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds. To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
09:36
Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
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2018
We present a workflow for segmenting and quantifying trabecular bones for 2D and 3D images based on the bone's outer boundary using an ImageJ plugin. This approach is more efficient and accurate than the current manual hand-contouring approach, and provides layer-by-layer quantifications, which are not available in current commercial software.
12:27
Piping Networks and Pressure Losses
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2023
Source: Alexander S Rattner, Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, University Park, PA This experiment introduces the measurement and modeling of pressure losses in piping networks and internal flow systems. In such systems, frictional flow resistance from channel walls, fittings, and obstructions causes mechanical energy in the form of fluid pressure to be converted to heat. Engineering analyses are needed to size flow hardware to ensure...
FAQs
Load sharing depends on the arrangement of trabecular plates and rods, including their thickness, spacing, connectivity, and orientation. This organized lattice distributes forces through the interior of a skeletal structure rather than concentrating them in one location. At the same time, the architecture preserves mechanical function without requiring the mass of a completely solid structure.
Osteoclasts remove existing bone tissue, while osteoblasts deposit new matrix. Their opposing activities produce continuous remodeling of the trabecular network. Local mechanical stresses and metabolic signals influence this activity, allowing the internal architecture to change over time. Imbalances in removal and deposition can therefore alter structural features relevant to skeletal strength and fracture risk.
Trabecular thickness, spacing, connectivity, and orientation provide complementary information about internal bone architecture. Thickness describes the size of individual elements, spacing indicates how far apart they are, connectivity reflects how well the elements form an integrated structure, and orientation shows their alignment. Examining these measures together helps relate microscopic organization to mechanical performance and fracture risk.
Imaging characterizes the internal architecture, whereas biomechanical analysis examines how that architecture relates to mechanical behavior. Investigators can evaluate structural measures such as thickness, spacing, connectivity, and orientation, then interpret them alongside load-distribution properties. This combination supports a more complete assessment than either structural observation or mechanical analysis alone, particularly when studying changes in skeletal health.
Research commonly examines this network in studies of osteoporosis, bone development, aging, and skeletal effects of exercise or disease. These settings can produce changes in internal architecture that are evaluated through imaging and biomechanical analyses. Comparing structural features across such conditions helps investigators investigate how biological processes and external influences relate to skeletal strength and fracture risk.
In osteoporosis research, measurements of trabecular thickness, spacing, connectivity, and orientation help characterize skeletal changes associated with reduced bone strength and fracture risk. Imaging provides information about internal structure, while biomechanical analyses connect those features with load distribution. Together, these approaches help investigate how remodeling and disease-related changes affect the mechanical condition of cancellous bone.