Hair Loss
Hair Loss - Related Videos
06:41
A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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Cited by 3 •
2015
Alopecia is a common form of hair loss which can occur in many different conditions, including as a side-effect of chemotherapy. We have developed a method to quantify hair loss in mice, utilizing a standard gel imager to perform a grayscale analysis, to facilitate study of promising new alopecia therapies.
01:22
Hair Cells
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2019
Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here. Hair cells are named after...
08:54
Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples
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Cited by 5 •
2020
Current methods of analyzing patients’ adherence to complex drug resistant-tuberculosis (DR-TB) regimens can be inaccurate and resource-intensive. Our method analyzes hair, an easily collected and stored matrix, for concentrations of 11 DR-TB medications. Using LC-MS/MS, we can determine sub-nanogram drug levels that can be utilized to better understand drug adherence.
01:10
Line Loss
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2024
The different configurations of source-load connections include wye (star) and delta connections. The relationship between line and phase voltages and currents varies depending on the configuration. When the source is supplying power, it is transmitted through the wires to the load, and during this transmission, some power is absorbed by the wires, leading to line loss. Line loss impacts power delivery efficiency in a balanced three-phase circuit. The symmetry in such a circuit simplifies the...
12:27
Piping Networks and Pressure Losses
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2023
Source: Alexander S Rattner, Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, University Park, PA This experiment introduces the measurement and modeling of pressure losses in piping networks and internal flow systems. In such systems, frictional flow resistance from channel walls, fittings, and obstructions causes mechanical energy in the form of fluid pressure to be converted to heat. Engineering analyses are needed to size flow hardware to ensure...
FAQs
Hair follicle cycling determines whether density is maintained over time. During anagen, follicles produce hair; catagen is a regression phase; and telogen is a resting or shedding phase. If these transitions become unbalanced, fewer follicles remain actively producing visible fibers, so researchers examine cycle timing and phase disruption when interpreting reduced hair density.
Androgen-driven miniaturization reduces the productive capacity of affected follicles, linking hormonal signaling to progressive thinning. This mechanism differs from direct immune-mediated damage, in which immune activity harms the follicle. Separating these pathways matters because inherited, inflammatory, and other forms of alopecia can produce hair loss through biologically different processes.
General health, nutritional status, and treatment exposure can alter follicle behavior without representing the same mechanism as androgen-driven miniaturization or immune attack. Considering these influences helps biology researchers distinguish potentially reversible or treatment-related changes from inherited or inflammatory patterns, improving interpretation of why growth has slowed or density has fallen.
Researchers can organize an investigation by asking which follicle process is altered, whether androgen-driven miniaturization or immune-mediated damage is implicated, and whether inherited, nutritional, inflammatory, treatment-related, or general-health factors fit the pattern. This mechanism-based approach supports distinguishing forms of alopecia and connects biological findings with diagnosis and treatment planning.
By connecting a form of alopecia to its underlying follicle biology, hair-loss research can help guide therapies intended either to support regrowth or to slow progression. The practical outcome is not a single treatment pathway, but a more targeted interpretation of whether the central problem involves cycling, miniaturization, immune-mediated damage, or another recognized context.
Studying hair loss provides a model for examining stem-cell activity, tissue regeneration, and skin health. Hair follicles are useful biological systems because changes in their growth, regression, and resting phases reveal how tissues renew and respond to genetic, hormonal, immune, or health-related influences. Findings therefore extend beyond scalp density to broader questions in biology.