Ovarian Hormones

Ovarian hormones are signaling molecules produced primarily by the ovaries that regulate reproductive function and influence tissues throughout the body. The principal hormones, estrogens and progesterone, are released in changing patterns across the ovarian cycle: developing follicles produce increasing estrogen, ovulation follows a midcycle gonadotropin surge, and the corpus luteum secretes progesterone during the luteal phase. Through feedback on the hypothalamus and pituitary, these hormones coordinate follicle development, ovulation, and preparation of the uterine lining for possible implantation. Studying ovarian hormones helps explain menstrual cycles, fertility, pregnancy, puberty, and hormone-related disorders, while supporting research into contraception and reproductive health.

Ovarian Hormones - Related Videos

Education

JoVE Core - Anatomy and Physiology

Hormonal Control of the Ovarian Cycle

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2024

The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction. Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...

Types of Hormones

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2019

Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells. Steroid hormones are derived from cholesterol and are lipophilic in nature. This allows them to readily traverse the lipid-rich cell membrane to bind to their intracellular receptors in the cytoplasm or nucleus. Once bound, the cytoplasmic hormone-receptor complex translocates to the nucleus.

Hormonal Regulation

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2019

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.

Plant Hormones

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2020

Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands. Instead, plant hormones are often produced in regions of active growth, like the tips of roots and shoots. Additionally, even very low concentrations of plant hormones can have a profound effect on growth and development processes.

Research

JoVE Journal - Biology

Blood Sampling and Hormone Measurement for Determining the Stage in the Ovarian Cycle in Marmosets

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2024

This protocol describes blood and urine sampling for measuring progesterone/estradiol and chorionic gonadotropin levels to determine the ovarian cycle stage. The hormone levels are used to predict and determine the timing of ovulation and hormones are injected to regulate the ovarian cycle and oocyte growth.

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