Temporal Bone

The temporal bone is a paired cranial bone that forms part of the lateral skull and cranial base, protecting structures essential for hearing, balance, and jaw movement. Its dense petrous portion encloses the middle and inner ear, while the external acoustic meatus channels sound toward the tympanic membrane; the mandibular fossa, mastoid process, and styloid process provide sites for articulation and muscle or ligament attachment. In biology and medicine, studying the temporal bone supports understanding of auditory and vestibular anatomy, temporomandibular joint function, skull development, and trauma. Detailed knowledge also guides imaging and procedures involving the ear, cranial nerves, and skull base.

Temporal Bone - Related Videos

Research

JoVE Journal - Developmental Biology
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Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

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2017

The segmentation clock drives oscillatory gene expression across the pre-somitic mesoderm (PSM). Dynamic Notch activity is key to this process. We use imaging and computational analyses to extract temporal dynamics from spatial expression data to demonstrate that Delta ligand and Notch receptor expression oscillate in the vertebrate PSM.

Research

JoVE Journal - Medicine

Extracting the Cochlea from a Human Temporal Bone: A Cadaveric Protocol

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2023

This article presents a reliable method for extracting the human cochlea from the cadaver temporal bone by drill-out while following distinct anatomical landmarks.

Models of Bone Metastasis

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Cited by 115 •

2012

Animal models are frequently utilized to study cancer metastasis to bone. In this protocol we will describe two common methods of tumor inoculation for bone metastasis studies and briefly describe some of the analyses utilized to monitor and quantify these models.

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

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2022

This article describes a technique for rapid human temporal bone sectioning that utilizes a microsaw with twin diamond blades to generate thin slices for rapid decalcification and analysis of temporal bone immunohistochemistry.

Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

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Cited by 293 •

2016

Here we present a protocol for the dissection of hind limb long bones (femurs and tibiae) from the laboratory mouse. We further describe a rapid technique for bone marrow isolation from these bones that utilizes centrifugation for removal of bone marrow from the bone marrow space.

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