Gate Valve

A gate valve is a mechanical device that starts or stops fluid flow by moving a barrier, or gate, through a pipeline, making it a fundamental component of fluid-control systems in engineering. When the valve operates, a handwheel, actuator, or stem raises or lowers the gate perpendicular to the flow path; a fully raised gate leaves a nearly unobstructed passage, while a lowered gate seals against valve seats. Gate valves are widely used in water treatment, oil and gas, power generation, and industrial process systems where reliable isolation and low flow resistance are important. They are generally suited to on-off service rather than flow throttling.

Gate Valve - Related Videos

Research

JoVE Journal - Behavior
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P50 Sensory Gating in Infants

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Cited by 5 •

2013

Methods to record auditory P50 sensory gating, a physiological marker of cerebral inhibition which reflects early stages of attention, are described.

Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification

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Cited by 16 •

2017

This protocol describes the isolation, culture, and calcification of rat-derived valve interstitial cells, a highly physiological in vitro model of calcific aortic valve disease (CAVD). Exploitation of this rat model facilitates CAVD research in exploring the cell and molecular mechanisms that underlie this complex pathological process.

Education

JoVE Core - Pharmacology
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Ligand-Gated Ion Channel Receptor: Gating Mechanism

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2023

Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...

Education

JoVE Core - Civil Engineering

Underflow Gates

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2025

Underflow gates are vital for controlling water flow in irrigation canals. The three main types of underflow gates — vertical, radial, and drum gates — serve different purposes while ensuring effective flow management. Vertical gates move up and down, generating a free-flowing water jet; radial gates pivot to regulate the flow; and drum gates rotate for precise adjustments. The flow through these gates is influenced by downstream conditions, resulting in free or drowned outflow.Free and Drowned...

Isolation of Mouse Valve Interstitial Cells: An Enzymatic Method to Isolate and Culture VICs from Mouse Aortic Valve

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2025

In this video, we demonstrate the isolation of aortic valve interstitial cells from the heart of an adult mouse using a two-step collagenase procedure and their subsequent culture in low volume of growth media.

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