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Immunology and Infection

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A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

Article DOI: 10.3791/60024-v • 07:40 min • August 30th, 2019
August 30th, 2019 •
1, 1, 1, 1
1Pulmonary and Critical Care Medicine, Department of Internal Medicine, Brigham and Women's Hospital, Harvard Medical School

章节

总结概括
Automatic Translation

Selective intra-bronchial acid instillation to the left lung in mice results in unilateral and self-limited acute lung injury that models human acute respiratory distress syndrome (ARDS) induced by gastric acid aspiration.

Tags

Self-limited Acute Lung Injury Unilateral Intra-bronchial Acid Instillation Acute Respiratory Distress Syndrome Selective Intra-bronchial Method Inflammatory Response Left Lung Right Lung Animal Distress Hydrochloric Acid Preparation PH Measurement Sodium Hydroxide Acid Stock Solution Sterile Microcentrifuge Tube Pain Reflex Anesthetized Mouse Surgical Area
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