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Advanced Biology

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Genetics

DNA Methylation and Gene Silencing

Description

DNA methylation is a DNA change that can help turn genes on or off. It happens most often at CpG dinucleotides, which are places where a cytosine is followed by a guanine in the DNA sequence. Methyl groups added at these sites may affect gene expression and are often studied near promoters and other gene control regions.

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Transcript

DNA-Methylierung ist eine chemische Modifikation der DNA, die gen-Expression in verschiedenen zellulären Kontexten betrifft. Viele Forscher sind der Mechanismus und die Funktionen dieses Prozesses interessiert wie aberranten DNA-Methylierung mit Krankheiten wie Krebs in Verbindung gebracht wurde.

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