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Genetics
DNA Methylation and Gene Silencing
Description
DNA methylation is a DNA change that can help turn genes on or off. It happens most often at CpG dinucleotides, which are places where a cytosine is followed by a guanine in the DNA sequence. Methyl groups added at these sites may affect gene expression and are often studied near promoters and other gene control regions.
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Transcript
DNA methylation is a chemical modification of DNA that affects gene expression under different cellular contexts. Many researchers are interested in the mechanism and functions of this process, as aberrant DNA methylation has been associated with diseases such as cancer.
In this video, we will cover the principles...
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