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Genetics

DNA Repair Tools for Genome Editing

Description

Genome editing uses DNA repair to make targeted changes in the genome. It works by creating a double-strand break in DNA with an engineered nuclease. The nuclease is guided to a chosen genomic site by a protein or an RNA that recognizes a specific sequence.

After the break, the cell tries to repa...

Transcript

Genome editing comprises techniques with which researchers can “edit” or change a specific DNA sequence. These methods rely on the creation of small “cuts” in DNA, which cells attempt to repair, often incompletely. In this manner, scientists can induce mutations in targeted sequences with greater efficiency compared to classic...

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