Frontal Cortex

The frontal cortex is the brain’s anterior cerebral region, containing areas that coordinate voluntary movement, decision-making, attention, language, and social behavior. Its neural circuits integrate sensory information, memories, and motivational signals, then regulate actions through communication with other cortical regions and subcortical structures. In biology and neuroscience, studying the frontal cortex helps explain executive function, motor control, learning, and behavioral flexibility. Research on its organization and activity also provides insight into how brain injury, neurological disease, and psychiatric conditions can alter cognition and behavior, supporting advances in brain mapping, clinical assessment, and targeted treatment.

Frontal Cortex - Related Videos

Research

JoVE Journal - Behavior
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Continuous Theta Burst Stimulation of the Posterior Medial Frontal Cortex to Experimentally Reduce Ideological Threat Responses

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Cited by 3 •

2018

Threats reliably evoke shifts in high-level ideological investment, but little work to date has explored the neural mechanisms underlying these dynamics. This paper describes how continuous theta burst transcranial magnetic stimulation may be employed to test the contribution of the posterior medial frontal cortex (and/or other regions) to threat-related ideological shifts.

Research

JoVE Journal - Medicine

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

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Cited by 3 •

2024

Here, we present a protocol to describe the epilepsy outcome and complications of 8 patients with mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) in the frontal lobe after frontal disconnection. The procedure is characterized by its simplicity, user-friendliness, and fewer postoperative complications.

Real-time fMRI Biofeedback Targeting the Orbitofrontal Cortex for Contamination Anxiety

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Cited by 32 •

2012

Here we present a method for training people to control a brain area involved in contamination anxiety and for probing the relationship between contamination anxiety and brain connectivity patterns.

Research

JoVE Journal - Neuroscience
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The Dig Task: A Simple Scent Discrimination Reveals Deficits Following Frontal Brain Damage

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Cited by 14 •

2013

In this protocol, a novel application of scent discrimination is described. The Dig task is a reasonably inexpensive task that can be used to assess frontally-mediated cognition following brain damage.

Generation of Medial Thalamus-Anterior Cingulate Cortex Slices from Mouse Brains

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2025

The video demonstrates the preparation of medial thalamus-anterior cingulate cortex (MT-ACC) slices from mouse brains. A mouse's brain is dissected, cuts are made to expose the MT-ACC pathway, and slices are generated using a vibratome. The MT-ACC slices are then maintained in oxygenated artificial cerebrospinal fluid.

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