Placenta Dissection
Placenta Dissection - Related Videos
14:42
Isolation and Analysis of Hematopoietic Stem Cells from the Placenta
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Cited by 11 •
2008
We have identified the placenta as a major hematopoietic organ during development. We found that hematopoietic stem cells (HSCs) are both generated and expanded in the placenta in unique microenvironmental niches. Here, we describe experimental techniques required for isolation and visualization of HSCs in the mouse placenta.
12:40
Isolation and Expansion of Mesenchymal Stem/Stromal Cells Derived from Human Placenta Tissue
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Cited by 91 •
2016
Herein we describe methods for the dissection of fetal and maternal tissues from human term placenta, followed by isolation and expansion of mesenchymal stem/stromal cells (MSC) from these tissues.
07:06
Isolation and Characterization of Mesenchymal Stromal Cells from Human Umbilical Cord and Fetal Placenta
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Cited by 171 •
2017
Here, we present a protocol for the dissection of human umbilical cord (UC) and fetal placenta sample into cord lining (CL), Wharton's jelly (WJ), cord-placenta junction (CPJ), and fetal placenta (FP) for the isolation and characterization of mesenchymal stromal cells (MSCs) using the explant culture technique.
09:52
Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
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Cited by 92 •
2011
Twin-to-twin transfusion syndrome and twin anemia polycythemia sequence are two potentially devastating problems in perinatal medicine. Both disorders occur only in monochorionic twins and result from unbalanced blood flow through placental vascular anastomoses. We provide a simple protocol to accurately evaluate the presence of vascular anastomoses using colored dye injection of placental vessels after birth.
08:08
Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model
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Cited by 56 •
2013
The ex vivo dual recirculating human placental perfusion model can be used to investigate the transfer of xenobiotics and nanoparticles across the human placenta. In this video protocol we describe the equipment and techniques required for a successful execution of a placenta perfusion.
FAQs
Comparing the fetal and maternal surfaces helps reveal how placental organization relates to its two-sided role. Examination of these surfaces, together with the membranes and umbilical cord, provides anatomical evidence about the interface supporting maternal-fetal exchange. In biology, this comparison connects visible structural features with oxygen and nutrient transfer rather than treating the placenta as uniform tissue.
Serial sections expose the internal arrangement of placental tissue and help identify sites of maternal-fetal exchange. A sequence of sections provides a more complete view than examining only an external surface, allowing investigators to relate internal organization to oxygen and nutrient transfer, fetal growth, pregnancy complications, and developmental outcomes.
Observed structural organization can be interpreted in relation to the placenta’s support of fetal development. Dissection allows investigators to connect tissue arrangement and exchange sites with oxygen and nutrient transfer, fetal growth, and developmental outcomes. This relationship makes structural observations useful when considering how pregnancy complications, disease, or injury may affect development.
The examination begins by inspecting the fetal and maternal surfaces, followed by the membranes and umbilical cord. These external and associated structures are assessed before serial sections are taken through the placental tissue. Following this sequence preserves a broad anatomical context and helps relate surface observations to the internal organization revealed later.
In reproductive biology, the method provides direct anatomical evidence of how a temporary organ supports fetal development. In pathology, examining tissue organization, membranes, surfaces, and the cord helps relate placental findings to disease or injury. These observations can then be considered alongside pregnancy complications and developmental outcomes to investigate possible structural associations.
Placenta dissection turns an otherwise temporary organ into a direct subject for studying anatomy, development, and health. Students and researchers can observe the fetal and maternal sides, membranes, cord, and internal sections, then connect those findings with maternal-fetal exchange. This makes abstract processes such as oxygen and nutrient transfer accessible through physical anatomical evidence.