Surgical Cannula Implantation

Surgical cannula implantation is a procedure that places a hollow tube into a defined body compartment or tissue to create controlled, repeatable access for biological studies. During implantation, the cannula is positioned at the target site and secured so researchers can deliver substances, collect samples, or monitor local responses without performing a new invasive procedure each time. In biology, this method supports experiments in neuroscience, physiology, pharmacology, and behavioral research, including localized drug administration and repeated sampling in living models. Careful targeting, stabilization, and maintenance are essential for reliable measurements and for limiting tissue disruption over the study period.

Surgical Cannula Implantation - Related Videos

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JoVE EoE - Neurotherapeutics

Cannula Implantation into the Cisterna Magna in a Mouse Model

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2025

Source: Xavier, A. L. R., et al. Cannula Implantation into the Cisterna Magna of Rodents. J. Vis. Exp. (2018)This video demonstrates the procedure for implanting a cannula into the cisterna magna of an anesthetized mouse. The technique involves guiding a needle-mounted cannula through the dura into the inverted triangular cisterna magna and securing it for targeted delivery into the cerebrospinal fluid.

Cannula Implantation into the Cisterna Magna of Rodents

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Cited by 134 •

2018

Here we describe a protocol to perform cisterna magna cannulation (CMc), a minimally invasive way to deliver tracers, substrates and signaling molecules into the cerebrospinal fluid (CSF). Combined with different imaging modalities, CMc enables glymphatic system and CSF dynamics assessment, as well as brain-wide delivery of various compounds.

Direct Cannula Implantation in the Cisterna Magna of Pigs

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Cited by 1 •

2021

This article presents a step-by-step protocol for the direct cannula implantation in the cisterna magna of pigs.

Surgical Implantation of Temperature Telemetric Monitoring System in Mouse Model: A Surgical Procedure to Implant Temperature Telemetric Device to Measure Mouse Core Body Temperature

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2025

In this video, we describe a surgical procedure to implant a temperature telemetric device in a mouse model to continuously measure its core body temperature.

Research

JoVE Journal - Biology
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Surgical Technique for the Implantation of a Biomimetic Artificial Intervertebral Disc in a Goat Animal Model

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2025

This study presents a novel surgical technique for implanting a biomimetic artificial intervertebral disc (BioAID). The method ensures precise placement and stability, aiming to restore cervical spine function using a goat model. This technique shows promise for clinical application in both human and canine patients suffering from cervical spine myelopathy.

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