Intra-aortic Balloon Pump

An intra-aortic balloon pump (IABP) is a temporary mechanical circulatory support device that assists a failing heart by improving coronary blood flow and reducing the workload of the left ventricle. A balloon catheter positioned in the descending thoracic aorta inflates during diastole to augment aortic pressure and coronary perfusion, then rapidly deflates just before systole to lower afterload and reduce myocardial oxygen demand. In clinical care, IABP support may stabilize selected patients with cardiogenic shock, acute myocardial infarction complications, or those undergoing high-risk cardiac procedures. Understanding its timing, physiology, and potential complications is essential for safe patient management.

Intra-aortic Balloon Pump - Related Videos

Research

JoVE Journal - Medicine

The Intra-Aortic Balloon Pump

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Cited by 8 •

2021

We describe the steps for the percutaneous implantation of the intra-aortic balloon pump (IABP), a mechanical circulatory support device. It acts by counterpulsation, inflating at the onset of diastole, augmenting diastolic aortic pressure and improving coronary blood flow and systemic perfusion, and deflating before systole, reducing left ventricular afterload.

Research

JoVE Journal - Medicine
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Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

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Cited by 84 •

2015

Subcutaneous implantation of osmotic pumps provides a convenient approach for prolonged and consistent delivery of compounds. This approach has been used extensively to study both abdominal and thoracic aortic aneurysms in mice.

A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury

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Cited by 2 •

2023

An appropriate animal model is needed to understand the pathologic mechanisms underlying aortic valve stenosis (AVS) and to evaluate the efficacy of therapeutic interventions. The present protocol describes a new procedure for developing the AVS rabbit model via a direct balloon injury in vivo.

Inducing Brain Death in a Mouse Model Using a Balloon Catheter

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2025

This video demonstrates the procedure for inducing brain death in a mouse model by increasing controlled intracranial pressure through a balloon catheter, mimicking natural brain death.

A New Murine Model of Endovascular Aortic Aneurysm Repair

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Cited by 3 •

2013

Histological and biochemical modifications after aneurysm endograft exclusion are still unclear. We describe a new model of endograft implantation on a murine aneurysm. Through thrombus analysis with and without persistant circulating blood stream interface, and new endovascular biomaterials evaluation, this model will help to better understand endovascular aneurysm exclusion pathobiology.

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