Diagonal Lines

Diagonal lines are straight lines that connect two points that do not lie directly above, below, or beside one another, and in geometry they commonly join nonadjacent vertices of a polygon. In a coordinate system, their orientation is described by slope, calculated as the change in vertical position divided by the change in horizontal position; this distinguishes diagonal direction from horizontal and vertical alignment. In engineering, diagonal lines represent braces, load paths, cut lines, and inclined members in technical drawings and computer-aided design. Understanding their length, angle, and intersections supports structural stability, accurate modeling, and spatial analysis.

Diagonal Lines - Related Videos

Research

JoVE Journal - Biology
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Diagonal Method to Measure Synergy Among Any Number of Drugs

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Cited by 37 •

2018

In this protocol, we describe how to make Loewe additivity-based drug interaction measurements for pairwise and three-way drug combinations.

Research

JoVE EoE - Neuronal Culture Techniques

Preparation of Colliculo-Thalamocortical Slices from a Mouse Pup Brain

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2025

The video demonstrates the preparation of colliculo-thalamocortical brain slices from mouse pup brains. An isolated brain is aligned on a marked slide and cut at an angle to align the auditory midbrain and forebrain in the same plane. The brain is then sliced using a vibratome, and the slices containing the major auditory midbrain and forebrain structures are transferred to a holding chamber for preservation.

Establishing a Whole-Cell Voltage-Clamp Configuration for Electrophysiological Recordings in Brain Slices

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2025

This video demonstrates positioning a fine-pointed pipette near brain slices, forming a seal with a neuronal cell. Suction breaks the cell membrane, thereby creating a whole-cell patch clamp that enables current measurements for electrophysiology experiments.

Two-Dimensional Semi-Denaturing Agarose Gel Electrophoresis: A Technique to Separate Polymorphic Amyloids Fibers Based on Size Heterogeneity

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2025

This video demonstrates the two-dimensional semi-denaturing detergent agarose gel electrophoresis-based separation of amyloid fibers. The technique separates the polymorphic amyloid aggregates based on their heterogeneous size.

Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging

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Cited by 8 •

2015

Using multiple angles to cut the mouse pup brain, we improve upon a previously-described acute brain slice which captures the connections between most of the major auditory midbrain and forebrain structures.

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