Pharmaceuticals Aquatic Environment

Pharmaceuticals in the aquatic environment are biologically active drug compounds and their transformation products present in surface water, groundwater, wastewater, or sediments, where they can become emerging contaminants. They enter through human and veterinary excretion, manufacturing discharges, runoff, and improper disposal, while conventional wastewater treatment may remove them incompletely; their persistence and behavior depend on chemical properties, degradation, sorption, and dilution. Monitoring these compounds helps assess exposure of aquatic organisms and potential ecological effects, including interference with physiological processes. The topic supports improved wastewater treatment, environmental risk assessment, pollution control, and strategies for safer pharmaceutical use and disposal.

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Research

JoVE Journal - Environment
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Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation

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Cited by 12 •

2018

We present a protocol for non-targeted analysis using time of flight mass spectrometry as a perfect tool to identify pharmaceuticals in waters. We demonstrate the application of UV irradiation for their elimination. Analysis involving irradiation, compound isolation, identification and kinetic modelling of the degradation profiles is illustrated.

Education

JoVE Science Education - Environmental Sciences

Nutrients in Aquatic Ecosystems

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2023

Source: Laboratories of Margaret Workman and Kimberly Frye - Depaul University Nitrogen and phosphorus are essential plant nutrients found in aquatic ecosystems and both are monitored as a part of water quality testing because in excess amounts they can cause significant water quality problems. Nitrogen in water is measured as the common form nitrate (NO3-) that is dissolved in water and readily absorbed by photosynthesizers such as algae. The common form of phosphorus measured is phosphate...

Failure of Cleaning Verification in Pharmaceutical Industry Due to Uncleanliness of Stainless Steel Surface

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Cited by 2 •

2017

The lack of a well-defined procedure that consistently cleaned coupon surfaces was identified as the major contributor to low and variable recoveries in cleaning verification. This manuscript describes the correct protocol of cleaning stainless steel coupons.

Characterization of Aquatic Biofilms with Flow Cytometry

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Cited by 8 •

2018

Flow cytometry in combination with visual clustering offers an easy-to-use and fast method for studying aquatic biofilms. It can be used for biofilm characterization, detection of changes in biofilm community structure, and detection of abiotic particles embedded in the biofilm.

Sampling, Sorting, and Characterizing Microplastics in Aquatic Environments with High Suspended Sediment Loads and Large Floating Debris

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Cited by 5 •

2018

Most microplastic research to date has occurred in marine systems where suspended solid levels are relatively low. Focus is now shifting to freshwater systems, which may feature high sediment loads and floating debris. This protocol addresses collecting and analyzing microplastic samples from aquatic environments that contain high suspended solid loads.

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