Liver Imaging
Liver Imaging - Related Videos
04:09
Imaging Fixture Supported Mouse Liver Staging for Multiphoton Microscopy Based Vascular Visualization: A Stabilization Device-assisted Imaging Technique to Obtain Multi-dimensional Images of Blood Vessels in Mouse Liver
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2025
This video describes an imaging procedure to observe and study intravascular dynamics of a mouse liver tissue using multiphoton microscopy following stabilization of the organ. Multiphoton microscopy enables the imaging of biological tissue at high spatial resolution in vivo.
10:48
Intravital Microscopy Imaging of the Liver following Leishmania Infection: An Assessment of Hepatic Hemodynamics
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Cited by 10 •
2015
This article reports on a detailed method for the dynamic measurement and quantification of blood flow velocity within individual blood vessels of the mouse liver vasculature using intravital microscopy imaging in combination with a specific methodology for image acquisition and analysis.
12:35
In vivo Liver Endocytosis Followed by Purification of Liver Cells by Liver Perfusion
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Cited by 14 •
2011
The study of liver sinusoidal endothelial cells (SECs) must be performed with primary cells obtained from the animal as no cell lines exist. This method relies on liver digestion and differential centrifugation for SEC purification for subsequent culturing and experimentation.
11:44
Long Term Intravital Multiphoton Microscopy Imaging of Immune Cells in Healthy and Diseased Liver Using CXCR6.Gfp Reporter Mice
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Cited by 27 •
2015
Stable intravital high-resolution imaging of immune cells in the liver is challenging. Here we provide a highly sensitive and reliable method to study migration and cell-cell-interactions of immune cells in mouse liver over long periods (about 6 hours) by intravital multiphoton laser scanning microscopy in combination with intensive care monitoring.
11:43
Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
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Cited by 6 •
2016
The ability of metastatic clones to colonize distant sites depends on their proliferation capacity and/or their ability to survive in the host microenvironment without significant proliferation. Here, we present an animal model that allows quantitative visualization of both types of liver colonization by metastatic clones.
FAQs
The modalities generate complementary information through different physical signals. Ultrasound uses reflected sound waves, computed tomography uses x-rays, and magnetic resonance imaging uses magnetic fields and radiofrequency signals. These differences affect how hepatic structure, blood flow, and disease-related changes are visualized, allowing investigators and clinicians to select or combine techniques according to the information needed.
Contrast agents enhance the visibility of vascular patterns and focal liver lesions. By increasing differences between tissues or between flowing blood and surrounding structures, they can make abnormalities easier to identify and characterize. This added information supports assessment of disease-related changes and can improve treatment planning when unenhanced images do not provide sufficient detail.
Imaging shows structural and anatomical consequences of disease, but it does not replace laboratory, microbiological, or tissue-based evidence. Combining these sources helps correlate visible abnormalities with infection, inflammation, immune-mediated injury, or other disease processes. This integrated approach is especially important when complex liver findings require both localization and biological characterization.
In immunology and infection research, imaging can reveal abscesses, inflammatory changes, biliary complications, and tissue injury associated with immune responses. These findings help connect local hepatic abnormalities with broader disease mechanisms. Imaging therefore provides a noninvasive way to evaluate affected tissue while complementary testing clarifies the infectious, inflammatory, or immune-related cause.
Liver imaging can identify the location and visible characteristics of abnormalities that require further investigation or intervention. This information helps guide targeted procedures toward relevant hepatic or biliary findings rather than relying only on indirect laboratory evidence. The resulting approach can improve correlation between the imaged lesion and subsequent microbiological or histopathological assessment.
Because imaging can document hepatic structure, blood flow, and disease-related changes over time, repeated examinations can support assessment of progression or response to therapy. In infection and immune-mediated disease, serial findings may show whether abnormalities persist, evolve, or improve. Interpretation remains strongest when imaging changes are considered alongside laboratory and clinical evidence.