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Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones
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Chapters
- 00:05Title
- 01:14Calibration of Fluorescent Signal Intensity as a Function of Cell Number
- 02:29Animal Model of Liver Metastases
- 05:44In Vivo Bioluminescent Imaging
- 07:58Ex Vivo Fluorescent Imaging
- 09:05Results: Metastases and Differential Liver Colonization of Colorectal Cancer Cells
- 10:34Conclusion
The ability of metastatic clones to colonize distant sites depends on their proliferation capacity and/or their ability to survive in the host microenvironment without significant proliferation. Here, we present an animal model that allows quantitative visualization of both types of liver colonization by metastatic clones.
