Subcutaneous Adipose Arterioles
Subcutaneous Adipose Arterioles - Related Videos
09:20
Isolation and Differentiation of Adipose-Derived Stem Cells from Porcine Subcutaneous Adipose Tissues
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Cited by 47 •
2016
This protocol describes the isolation of pig adipose-derived stem cells (pADSC) from subcutaneous adipose tissues with examination of multipotency. The multipotent pADSC are used to delineate processes of adipocyte differentiation and study transdifferentiation into multiple cell lineages of mesodermal mesenchyme or further lineages of ectoderm and endoderm for regenerative studies.
09:01
A Technique for Subcutaneous Abdominal Adipose Tissue Biopsy via a Non-diathermy Method
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Cited by 7 •
2017
We standardized an abdominal adipose tissue biopsy using a non-diathermy method performed under local anesthesia. Three cases of excessive post-operation bleeding out of 115 operations (2.61%) occurred.We conclude that an abdominal adipose tissue surgical biopsy using a non-diathermy method can be safely applied to healthy men.
09:49
Isolation and Cannulation of Cerebral Parenchymal Arterioles
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Cited by 28 •
2016
This manuscript describes a simple and reproducible protocol for isolation of intracerebral arterioles (a group of blood vessels encompassing parenchymal arterioles, penetrating arterioles and pre-capillary arterioles) from mice, to be used in pressure myography, immunofluorescence, biochemistry, and molecular studies.
03:41
Preparing Cerebral Endothelial Tubes from Mouse Parenchymal Arterioles
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2025
This video demonstrates a method for isolating the endothelial tubes from mouse cerebral parenchyma. Through a combination of enzymatic digestion and mechanical dissociation, the process yields an intact tube with endothelial cells.
06:35
Studying Adipose Endothelial Cell/Adipocyte Cross-Talk in Human Subcutaneous Adipose Tissue
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2024
Here, we describe a protocol for isolating, culturing, and phenotyping microvascular endothelial cells from human subcutaneous adipose tissue (hSATMVECs). Additionally, we describe an experimental model of hSATMVEC-adipocyte cross-talk.
FAQs
These signals act on vascular smooth muscle, changing the diameter of the arteriole. Diameter changes alter resistance to blood flow, so the tissue can receive different amounts of oxygen, nutrients, and waste-product exchange. Examining these coordinated responses helps explain how adipose perfusion adjusts to both systemic regulation and local metabolic needs.
Vascular smooth muscle provides the adjustable component of the vessel wall. When its tone changes, the arteriole becomes a variable resistance point that influences arterial inflow and tissue perfusion. This relationship connects cellular vessel behavior with broader outcomes such as oxygen delivery, metabolic exchange, and regulation of blood pressure.
Impaired vascular responses can disrupt the regulation of blood flow into subcutaneous fat and interfere with oxygen delivery and the exchange of nutrients and waste products. Studying these changes is therefore relevant to understanding how obesity, diabetes, and inflammation are associated with altered adipose biology and vascular dysfunction.
Their responses provide a way to examine how vascular regulation contributes to adipose tissue function. Findings can clarify relationships among vessel diameter, perfusion, metabolic exchange, and vascular dysfunction. This makes the vessels useful for investigating the vascular mechanisms associated with obesity, diabetes, inflammation, and other changes in metabolic health.
Because they regulate blood delivery to tissue beneath the skin, their responses can provide insight into processes that depend on controlled local perfusion. The source specifically identifies thermoregulation and wound healing as clinically relevant contexts, linking arteriolar function with the delivery and exchange conditions required by adipose tissue.
Observations from subcutaneous adipose arterioles can help connect microscopic changes in vessel regulation with clinically important conditions. They may clarify vascular mechanisms underlying metabolic disease and help interpret how obesity, diabetes, or inflammation alter adipose biology. Their relevance also extends to blood pressure regulation, tissue perfusion, thermoregulation, and wound healing.