Ultrasound-guided Injection
Ultrasound-guided Injection - Related Videos
08:22
Ultrasound-guided Transthoracic Intramyocardial Injection in Mice
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Cited by 16 •
2014
Echocardiography-guided percutaneous intramyocardial injection represents an efficient, reliable, and targetable modality for the delivery of gene transfer agents or cells into the murine heart. Following the steps outlined in this protocol, the operator can quickly become competent in this versatile, minimally invasive technique.
05:04
An Ultrasound-Guided Injection of Therapeutic Drugs into Human Salivary Glands
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2025
The video demonstrates an ultrasound-guided injection technique for administering therapeutic drugs into the salivary glands of a human patient.
07:05
Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
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Cited by 21 •
2016
Botulinum toxin is injected into the salivary glands for the treatment of sialorrhea. The ultrasound-guided botulinum toxin injection in both the parotid and submandibular glands demonstrates a sustained efficacy and the absence of serious side effects.
08:36
Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI
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Cited by 26 •
2014
A breast cancer brain metastasis mouse model is established with ultrasound imaging-guided intracardiac injection of MDA-MB231/Br-GFP cells. Development of multifocal intracranial metastases has been monitored longitudinally using high-resolution 9.4 T MRI.
07:47
Ultrasound-Guided Microinjection into the Mouse Forebrain In Utero at E9.5
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Cited by 16 •
2010
In utero survival surgery in mice permits the molecular manipulation of gene expression during development. Here we describe the use of high-frequency ultrasound imaging to guide the injection of retroviral vectors into the mouse brain at embryonic day (E) 9.5.
FAQs
The probe sends high-frequency sound waves into the body, and tissue interfaces reflect echoes back to the device. These returning signals are converted into an image that displays relevant anatomy and the advancing needle in real time. The operator can therefore monitor needle position continuously and make adjustments before delivering the substance at the intended target.
Seeing nerves, blood vessels, and other surrounding structures helps the operator distinguish the intended target from nearby anatomy. This spatial information supports more precise needle advancement and helps reduce unintended tissue injury. In neuroscience and pain research, such visualization is especially relevant when injections are directed near peripheral nerves or other sensitive neural structures.
Real-time imaging allows needle position to be assessed throughout the approach rather than only before or after delivery. If the needle does not align with the intended site, the operator can adjust its position while viewing the target and surrounding anatomy. This ongoing feedback supports localized delivery and improves control over where the substance is administered.
The procedure begins by positioning the ultrasound probe to visualize the target region and nearby anatomy. The operator then monitors the needle as it advances toward the selected site, using the live image to guide any needed adjustments. Once the needle reaches the intended location, the substance is delivered while the anatomy remains under observation.
Researchers may use ultrasound-guided injection when they need to place a substance near a peripheral nerve or another relevant neural structure. The approach supports localized drug delivery and nerve blockade, making it useful for examining how targeted interventions affect neural function. Continuous anatomical visualization also helps link the intervention to the intended site.
In neural studies, the technique can support three related outcomes: placing a substance at a selected anatomical site, producing a localized nerve blockade, and investigating neural function. Because the operator can monitor surrounding anatomy and needle position, the resulting intervention is more closely tied to the intended nerve or structure, helping researchers interpret localized effects.