Aging Studies
Aging Studies - Related Videos
06:08
Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
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Cited by 11 •
2014
Pulse wave velocity (PWV) measurement assesses arterial stiffness by a tonometry-based system that measures the speed with which arterial pressure wave travels along the arterial tree, typically approximating the time that it takes this wave to travel from the descending aorta (using the carotid artery as a surrogate) to the femoral artery. Carotid-femoral PWV increases two- to threefold across the adult lifespan.
08:46
Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model
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Cited by 13 •
2011
Here we describe a set of DNA mutation assays that can be combined with the yeast chronological life span model to study the genes/pathways that regulate or contribute to genomic DNA instability during aging.
14:57
Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Cited by 62 •
2011
This article outlines procedures for preparing hippocampal slices from rats and transgenic mice for the study of synaptic alterations associated with brain aging and age-related neurodegenerative diseases, such as Alzheimer’s disease.
11:57
Methods to Study Changes in Inherent Protein Aggregation with Age in Caenorhabditis elegans
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Cited by 7 •
2017
The goal of the method presented here is to explore protein aggregation during normal aging in the model organism C. elegans. The protocol represents a powerful tool to study the highly insoluble large aggregates that form with age and to determine how changes in proteostasis impact protein aggregation.
09:14
An Introduction to Aging and Regeneration
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2023
Tissues are maintained through a balance of cellular aging and regeneration. Aging refers to the gradual loss of cellular function, and regeneration is the repair of damaged tissue generally mediated by preexisting adult or somatic stem cells. Scientists are interested in understanding the biological mechanisms behind these two complex processes. By doing so, researchers may be able to use somatic stem cells to treat degenerative diseases and develop therapies that could delay the effects of...
FAQs
Researchers distinguish age-related patterns from cohort effects by examining whether an observed difference reflects change associated with age or characteristics shared by people who grew up during the same period. This distinction matters because a contrast between older and younger participants may reflect historical or social experiences rather than aging itself, improving interpretation of psychological findings.
Longitudinal designs can reveal patterns of change within people across time, whereas cross-sectional designs compare people at different ages. Using these approaches together helps psychologists interpret whether cognitive, emotional, behavioral, or social differences represent developmental change, cohort effects, or individual variation. The design choice therefore shapes how confidently researchers explain age-related findings.
Individual differences prevent researchers from treating age as the sole explanation for psychological outcomes. Health, environment, relationships, and socioeconomic conditions can contribute to variation in cognitive, emotional, behavioral, and social functioning. Considering these influences produces a more precise account of later-life development and helps explain why people of the same age may experience different levels of well-being.
A psychology assessment may examine cognitive, emotional, behavioral, and social changes while also recording relevant health, environmental, relationship, and socioeconomic conditions. Researchers can then analyze these measures with longitudinal or cross-sectional designs. This combination links observed psychological patterns to both age-related processes and the circumstances that shape individual development and well-being.
Findings can support strategies aimed at promoting mental health, independence, social connection, and quality of life among older adults. Psychological evidence is especially useful when it identifies how cognitive, emotional, behavioral, and social changes relate to health or relationships. These results help connect lifespan research with practical efforts to support well-being in later life.
An interdisciplinary perspective connects psychological changes with health, environmental conditions, relationships, and socioeconomic circumstances. This broader view recognizes that development and well-being in later life do not arise from one domain alone. Within psychology, it strengthens lifespan theories by situating cognitive, emotional, behavioral, and social findings within the varied conditions surrounding older adults.