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Journal / Immunology and Infection / Højkapacitetsforskning Assay til Fænotype
JoVE Journal
Immunology and Infection

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Højkapacitetsforskning Assay til Fænotype

Article DOI: 10.3791/51759-v • 11:10 min • August 11th, 2014
August 11th, 2014 •
1, 1, 1, 2, 3, 4, 1
1Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 2Department of Microbial and Molecular Pathogenesis, College of Medicine, Texas A&M University System Health Science Center, 3University of California, Irvine, 4Department of Medical Microbiology & Immunology, School of Medicine, University of California, Davis

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En høj-throughput assay til in vitro-fænotype salmonella eller andre bakterielle forening, invasion og replikation i fagocytiske celler med højt gennemløb kapacitet blev udviklet. Metoden blev anvendt til at vurdere Salmonella gen knockout mutantstammer for deres Involvering i værtspatogene interaktioner.

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Smitsomme sygdomme , forening invasion replikering fænotype intracellulære patogener makrofager
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