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Vaskulær Balloon Injury og Intraluminal Administration i Rat arteria carotis

Article DOI: 10.3791/52045-v • 09:41 min • December 23rd, 2014
December 23rd, 2014 •
1, 1
1Nanobioscience, State University of New York College of Nanoscale Science and Engineering (SUNY CNSE)

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Denne protokollen bruker en ballong kateter for å forårsake en intraluminal skade på rotte halspulsåren og heretter lokke fram neointimal hyperplasia. Dette er en veletablert modell for å studere mekanismene for vaskulær remodellering som respons på skade. Det er også mye brukt for å bestemme gyldigheten av potensielle terapeutiske tilnærminger.

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Medisin Rat halspulsåren ballong skade neointima vaskulær sykdom dyremodell vaskulær glatt muskelcelle hyperplasi vaskulær vegg ombygging
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