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Immunology and Infection

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Urinary Tract Infection in a Small Animal Model
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Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

Article DOI: 10.3791/54432-v • 10:23 min • December 1st, 2017
December 1st, 2017 •
1, 1,2, 1
1Unité d’Immunobiologie des Cellules Dendritiques, Department of Immunology, Institut Pasteur, INSERM U818, 2Genentech

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Summary
Automatic Translation

The established model of transurethral catheterization of mice allows the study of bladder pathologies, including urinary tract infection, but can only be performed in females. A new model of male transurethral instillation, presented here, will enable research in an area marked by strong clinical and epidemiological differences between the sexes.

Tags

Urinary Tract Infection Small Animal Model Transurethral Catheterization Male Mice Female Mice Immune Response Mucosal Immunology Natural Root Infection Bladder Cancer Pediatric Intravenous Access Canula Sterilize Catheters Uropathogenic E Coli (UPEC) Bacterial Suspension CFU Per Milliliter LB Agar
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