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Journal / Bioengineering / Modelleren van eierstokkanker Meercellige…
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Bioengineering

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Modelleren van eierstokkanker Meercellige Sferoïde Gedrag in een dynamische 3D peritoneale microdevice

Article DOI: 10.3791/55337-v • 11:34 min • February 18th, 2017
February 18th, 2017 •
*1, *1, *2, 2, 3, 3, 4, 2, 1
1School of Biological Sciences, University of Hong Kong, 2Department of Mechanical Engineering, University of Hong Kong, 3Department of Medicine, University of Hong Kong, 4Department of Biomedical Sciences, Key Laboratory of Biochip Technology, Biotech and Health Centre, Shenzhen Research Institutes of City University of Hong Kong
* These authors contributed equally

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Summary
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Ovariële tumorprogressie te bestuderen in een fysiologisch relevante model multicellulaire sferoïden werden gekweekt in een micro-inrichting onder gesimuleerde fluïdumstroming. Deze dynamische 3D-model emuleert de intraperitoneale omgeving met de cellulaire en mechanische componenten, waar eierstokkanker metastase optreedt.

Tags

Bioengineering eierstokkanker microfluidics shear stress peritoneale mesotheelcellen meercellige sferoïden 3D-cultuur de co-cultuur
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