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Genetics

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JoVE Journal Genetics
Genoom-wide mapping van eiwit-DNA-interacties met ChEC-seq in
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Genoom-wide mapping van eiwit-DNA-interacties met ChEC-seq in

Article DOI: 10.3791/55836-v • 10:43 min • June 3rd, 2017
June 3rd, 2017 •
1, 2
1Basic Sciences Division, Fred Hutchinson Cancer Research Center, 2Department of Biology, Indiana University

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We beschrijven chromatin endogene splitsing gekoppeld aan high-throughput sequencing (ChEC-seq), een chromatine immunoprecipitatie (ChIP) -orthogonale methode voor het mappen van eiwitbindingsplaatsen genoom-wijd met micrococculaire nuclease (MNase) fusie-eiwitten.

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Genetica ChEC-seq ChIP-seq transcriptie genoom-breed mediator,
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