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Journal / Bioengineering / Fremstilling og karakterisering af…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Fremstilling og karakterisering af Griffithsin-ændret Fiber stilladser til forebyggelse af seksuelt overførte infektioner
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Journal (Bioengineering)
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Three-dimensional Biomimetic Technology: Novel Biorubber Creates Defined Micro- and Macro-scale Architectures in Collagen Hydrogels
Journal (Bioengineering)
Three-dimensional Biomimetic Technology: Novel Biorubber Creates Defined Micro- and Macro-scale Architectures in Collagen Hydrogels
 
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Fremstilling og karakterisering af Griffithsin-ændret Fiber stilladser til forebyggelse af seksuelt overførte infektioner

Article DOI: 10.3791/56492-v • 12:21 min • October 31st, 2017
October 31st, 2017 •
*1, *2,3, 2,3,4,5
1Department of Chemistry, University of Louisville, 2Department of Pharmacology and Toxicology, University of Louisville, 3Center for Predictive Medicine, University of Louisville, 4Department of Microbiology and Immunology, University of Louisville, 5Department of Bioengineering, University of Louisville
* These authors contributed equally

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Dette manuskript beskriver proceduren, at fabrikere og karakterisere Griffithsin modificerede poly (mælkesyre-co-glycolic acid) electrospun fibre, der demonstrerer potent klæbende og antiviral aktivitet mod human immundefekt virus type 1-infektion i vitro. Metoder, der anvendes til at syntetisere, overflade-redigere, karakteriserer den resulterende morfologi, konjugering, og desorption for Griffithsin fra overfladen-modificerede fibre er beskrevet.

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Bioteknologi spørgsmålet 128 Electrospun fibre seksuelt overførte infektioner human immundefekt virus overflade-ændring microbicider Griffithsin poly (mælkesyre-co-glycolic acid)
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