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Journal / Bioengineering / 用三种互补方法综合评价胎盘靶向药物的有效性和安全性…
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Bioengineering

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JoVE Journal Bioengineering
用三种互补方法综合评价胎盘靶向药物的有效性和安全性
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用三种互补方法综合评价胎盘靶向药物的有效性和安全性

Article DOI: 10.3791/58219-v • 09:04 min • September 10th, 2018
September 10th, 2018 •
1, 1,2, 1,3, 1, 4, 1
1Laboratory for Reproductive Health, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 2College of Veterinary Medicine, Hunan Agricultural University, 3Key Laboratory of Chemical Engineering Process and Technology for High-efficiency Conversion, College of Chemistry and Material Sciences, Heilongjiang University, 4Department of Obstetrics and Gynecology, Wayne State University School of Medicine

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我们描述一个系统, 利用三方法来评估胎盘靶向药物的安全性和有效性:在体内成像监测纳米微粒积累, 高频超声监测胎盘和胎儿发育, 并以 HPLC 量化药物对组织的传递。

Tags

生物工程 139 期,体内成像 高频超声 高效液相色谱 胎盘硫酸软骨素 A 结合肽 纳米颗粒 胎盘靶向 妊娠并发症
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