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Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

Article DOI: 10.3791/63094-v • 08:56 min • September 24th, 2021
September 24th, 2021 •
1, 2, 3, 4, 4, 1, 1, 5, 1, 1,6, 5,7, 1,5
1Laboratory of Physiopharmacology, University of Antwerp, 2Department of Cardiac Surgery, University Hospital Antwerp, 3Department of Animal Welfare, University of Antwerp, 4Comparative Perinatal Development, University of Antwerp, 5Department of Cardiology, University Hospital Antwerp, 6Department of Cardiology, ZNA Middelheim Hospital, 7Research Group Cardiovascular Diseases, GENCOR, University of Antwerp

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Summary
Automatic Translation

We describe a sterile pericarditis model in minipigs to study atrial myopathy and atrial fibrillation (AF). We present surgical and anesthetic techniques, strategies for vascular access, and a protocol to study the inducibility of AF.

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Sterile Pericarditis Aachener Minipigs Atrial Myopathy Atrial Fibrillation Large Animal Model Pathogenesis Electrophysiology Studies Anatomy And Physiology Minipig Model Pathophysiology Pre-clinical Drug Discovery Pressure Conducting System Heparin IV Bag Femoral Artery Ultrasound Guidance Seldinger Technique Arterial Blood Pressure Monitoring Incision Sternocleidomastoid Muscle
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