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Journal / Bioengineering / Generazione, screening ad alto rendimento e…
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Bioengineering

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JoVE Journal Bioengineering
Generazione, screening ad alto rendimento e biobanca di sferoidi cardiaci derivati da cellule staminali pluripotenti indotte dall'uomo
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Generazione, screening ad alto rendimento e biobanca di sferoidi cardiaci derivati da cellule staminali pluripotenti indotte dall'uomo

Article DOI: 10.3791/64365-v • 09:23 min • March 10th, 2023
March 10th, 2023 •
1, *1, *1, 1, 1, 1, 1, 1, 2, *1, *1
1Utrecht Regenerative Medicine Center, Circulatory Health Laboratory, University Utrecht, Department of Cardiology, University Medical Center Utrecht, 2Amsterdam Cardiovascular Sciences, Department of Physiology, Amsterdam University Medical Center
* These authors contributed equally

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Qui viene presentato un insieme di protocolli per la generazione e la crioconservazione di sferoidi cardiaci (CS) da cardiomiociti derivati da cellule staminali pluripotenti indotti dall'uomo coltivati in un formato multidimensionale ad alto rendimento. Questo modello tridimensionale funziona come una solida piattaforma per la modellazione delle malattie, gli screening ad alto rendimento e mantiene la sua funzionalità dopo la crioconservazione.

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Bioingegneria Numero 193
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