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Genetics
DNA Methylation and Gene Silencing
Description
DNA methylation is a DNA change that can help turn genes on or off. It happens most often at CpG dinucleotides, which are places where a cytosine is followed by a guanine in the DNA sequence. Methyl groups added at these sites may affect gene expression and are often studied near promoters and other gene control regions.
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Transcript
Metilación del ADN es una modificación química del ADN que afecta la expresión génica en diferentes contextos celulares. Muchos investigadores están interesados en el mecanismo y funciones de este proceso, como la metilación aberrante del ADN se ha asociado con enfermedades como el cáncer.
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