Utero-tubal Junction

The utero-tubal junction is the narrow anatomical passage connecting the uterus with each fallopian tube, where it regulates the movement of sperm, oocytes, and early embryos and therefore supports mammalian reproduction. Its muscular wall, epithelial lining, and mucosal folds create a selective gateway: smooth-muscle contractions, ciliary activity, and hormonally regulated secretions influence transport through the junction and may help control the timing and direction of passage. Studying the utero-tubal junction helps explain sperm migration, fertilization, and early embryo movement, while providing biological insight into infertility, contraception, and reproductive tract disorders.

Utero-tubal Junction - Related Videos

Research

JoVE Journal - Biology

Utero-tubal Embryo Transfer and Vasectomy in the Mouse Model

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Cited by 25 •

2014

Utero-tubal embryo transfer uses the utero-tubal junction as a barrier to prevent the embryo outflow that may occur when performing uterine transfer. Vasectomized males are required to obtain pseudopregnant recipients for embryo transfer. Both techniques are discussed.

Education

JoVE Science Education - Advanced Biology

Murine In Utero Electroporation

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2023

In utero electroporation is an important technique for studying the molecular mechanisms that guide the proliferation, differentiation, migration, and maturation of cells during neural development. Electroporation enables the rapid and targeted delivery of material into cells by utilizing electrical pulses to create transient pores in cell membranes. Although electroporation has traditionally been used in in vitro studies, scientific advancements have now broadened its utilization to intact...

Papanicolaou Staining: A Technique to Visualize the Cytological Features of Tubal Cells

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2025

In this video, we demonstrate a modified protocol of Papanicolaou staining to study tubal cytology. This technique can be used to visualize the cytological features of malignant and non-malignant fallopian tube epithelial cells.

A Mouse Model of in Utero Transplantation

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Cited by 26 •

2011

The mouse model of in utero transplantation is a versatile tool that can be used to study the potential clinical applications of stem cell transplantation and gene therapy in the fetus. In this protocol, we present a general approach to performing this...

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection

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Cited by 11 •

2017

We explored a tubal cytologic method by sampling the fallopian tube directly post-surgical excision as a tool of ovarian cancer early detection. Here, we present a protocol to collect fallopian tube cells from freshly received surgical specimens.

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