Infection Control
Infection Control - Related Videos
03:04
An Intragastric Gavage Technique for Controlled Helicobacter Infection in Mice
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2025
This video demonstrates the establishment of Helicobacter pylori infection through the intragastric gavage technique in a mouse model. The bacterial suspension is administered via a catheter inserted through the mouth into the stomach. Inoculated bacteria colonize and establish an infection in the stomach, which can be used to study the host-pathogen interaction.
11:18
Infection of Zebrafish Embryos with Intracellular Bacterial Pathogens
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Cited by 234 •
2012
Transparent zebrafish embryos have proved useful model hosts to visualize and functionally study interactions between innate immune cells and intracellular bacterial pathogens, such as Salmonella typhimurium and Mycobacterium marinum. Micro-injection of bacteria and multi-color fluorescence imaging are essential techniques involved in the application of zebrafish embryo infection models.
12:30
Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection
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Cited by 108 •
2013
The larva of the wax moth Galleria mellonella was recently established as an in vivo model to study Legionella pneumophila infection. Here, we demonstrate fundamental techniques to characterize the pathogenesis of Legionella in the larvae, including inoculation, measurement of bacterial virulence and replication as well as extraction and analysis of infected hemocytes.
12:38
4D Multimodality Imaging of Citrobacter rodentium Infections in Mice
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Cited by 19 •
2013
Multi-modality imaging is a valuable approach for studying bacterial colonization in small animal models. This protocol outlines infection of mice with bioluminescent Citrobacter rodentium and the longitudinal monitoring of bacterial colonization using composite 3D diffuse light imaging tomography with μCT imaging to create a 4D movie of C. rodentium infection.
07:59
Bioluminescence Imaging to Detect Late Stage Infection of African Trypanosomiasis
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Cited by 3 •
2016
This manuscript describes the use of a bioluminescent strain of African trypanosomes to enable the tracking of late stage infection and demonstrates how in vivo live imaging can be used to visualize infections within the central nervous system in real-time.
FAQs
Interrupting transmission requires coordinated barriers at several points rather than reliance on one precaution. Hand hygiene and personal protective equipment limit transfer between people, while environmental cleaning, sterilization, and safe injection practices address contaminated surroundings or procedures. Isolation and vaccination add further protection, helping break the chain of infection across clinical and community settings.
Hand hygiene and protective equipment serve different but complementary functions. Hand hygiene reduces transfer associated with contact, whereas protective equipment provides a barrier during care. Their value depends on consistent use within a broader protocol, because infection control combines multiple practices instead of treating any single measure as sufficient.
Surveillance, staff training, and consistent adherence make infection control an active quality-improvement process. Surveillance helps organizations track infection-related patterns, training builds consistent practice, and adherence determines whether protocols work in routine care. Together, these elements support earlier recognition of problems, outbreak response, and efforts to limit antimicrobial-resistant organisms.
A practical approach begins with risk assessment, followed by selection of appropriate precautions for the care situation. Teams then apply relevant measures, such as hand hygiene, protective equipment, isolation, safe injections, environmental cleaning, or sterilization. Surveillance and staff training reinforce implementation, while adherence to evidence-based protocols supports consistent performance and quality improvement.
These practices matter throughout diagnosis, treatment, and surgery, where preventing transmission protects patients and healthcare workers. Isolation and other precautions become particularly relevant when transmission risks require separation or added barriers. Infection control also supports outbreak response and public health preparedness, extending its value beyond individual encounters to wider community protection.
Environmental cleaning, sterilization, and safe injection practices target different parts of clinical care. Cleaning addresses the care environment, sterilization supports safer procedures, and safe injection practices strengthen protection during injections. Using them together complements hand hygiene and protective equipment, helping reduce transmission risks during treatment and surgery.