Aortic Dilation
Aortic Dilation - Related Videos
12:17
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
0 Views •
Cited by 4 •
2017
Full-root aortic valve replacement by stentless aortic xenograft is a viable option in patients with small aortic roots. We describe, a technique for the full-root implantation of stentless aortic xenografts, with emphasis on the management of the proximal suture line and coronary anastomoses, and discuss its limitations and alternative options.
09:12
Aortic Ring Assay
0 Views •
Cited by 42 •
2009
Angiogenesis, the sprouting of blood vessels from pre-existing vasculature, is associated with both natural and pathological processes. Here we demonstrate an aortic ring assay that allows angiogenic potentiators and inhibitors to be directly added to aortic rings in culture. Sprouting and neovessel outgrowth can be determined by inspecting the aortic rings over a period of 6-12 days.
08:25
Transverse Aortic Constriction in Mice
0 Views •
Cited by 263 •
2010
Transverse aortic constriction (TAC) in the mouse is a commonly used experimental model to study mechanisms underlying cardiac hypertrophy and heart failure development. Here, we describe procedures to constrict the aorta to create a reproducible degree of cardiac hypertrophy in mice.
10:23
Creation of Murine Experimental Abdominal Aortic Aneurysms with Elastase
0 Views •
Cited by 55 •
2009
This video shows how to induce abdominal aortic aneurysms (AAA) in mice via transient intraluminal infusion of porcine pancreatic elastase into the infrarenal segment of the abdominal aorta. The model has the ability to add broad insight into the pathobiology of AAA due to the emergence of numerous transgenic and gene knockout mice.
07:21
Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
0 Views •
Cited by 84 •
2015
Subcutaneous implantation of osmotic pumps provides a convenient approach for prolonged and consistent delivery of compounds. This approach has been used extensively to study both abdominal and thoracic aortic aneurysms in mice.
FAQs
Progression can reflect weakening of the aortic wall’s connective-tissue framework and loss of elastic integrity. These structural changes reduce the wall’s ability to withstand repeated pressure from circulating blood, allowing the vessel to expand over time. Understanding this mechanism helps clinicians interpret changes in aortic size and consider how underlying conditions may influence an individual’s risk.
Blood pressure applies continual force to the aortic wall. When the wall has already lost structural strength or elasticity, that repeated stress can support further enlargement. Blood pressure management therefore forms an important part of care, because controlling this contributor may help reduce progression and the complications associated with increasing aortic size.
As the aortic wall expands and its structural integrity becomes compromised, it may become less able to tolerate ongoing mechanical stress. This creates concern for serious complications, including dissection or rupture. The clinical significance of a measured enlargement therefore depends not only on size, but also on its progression, associated symptoms, and the patient’s underlying conditions.
These imaging techniques provide ways to evaluate aortic size and monitor changes over time. Echocardiography, computed tomography, and magnetic resonance imaging can support clinical assessment, while the choice of imaging approach is considered alongside symptoms and underlying conditions. Repeated assessment helps clinicians evaluate progression and guide individualized surveillance or treatment decisions.
Monitoring decisions incorporate the measured aortic size, evidence of growth, symptoms, and underlying medical conditions. These factors help clinicians determine how closely a patient should be followed and whether management should remain focused on surveillance and blood pressure control. The approach is individualized because the clinical context influences the significance of imaging findings and progression.
Selected patients may require an intervention when clinical assessment indicates that surveillance and medical management alone are not sufficient. Surgical and endovascular procedures are treatment options used according to the individual situation, including imaging findings, progression, symptoms, and underlying conditions. Their role is to help reduce the likelihood of serious complications while tailoring care to the patient.