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Analys av Dendritiska Spine Morfologi i odlade CNS Neuroner

Article DOI: 10.3791/2794-v • 11:49 min • July 13th, 2011
July 13th, 2011 •
1, 1, 1,2
1Department of Physiology, Northwestern University Feinberg School of Medicine, 2Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine

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Många nyare studier har identifierat mutationer i synaptiska proteiner associerade med hjärnan sjukdomar. Primär odlade kortikala neuroner ger stor flexibilitet för att undersöka effekterna av dessa sjukdomar associerade proteiner på dendritiska ryggraden morfologi och motilitet.

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Neurovetenskap excitatoriska synapsen neurovetenskap hjärnan cortex kortikala neuroner primär kultur konfokalmikroskopi tidsförlopp avbildning ombyggnad.
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