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JoVE Journal Neuroscience
Intracerebroventricular behandling med resiniferatoxin og smertetest hos mus
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Intracerebroventricular behandling med resiniferatoxin og smertetest hos mus

Article DOI: 10.3791/57570-v • 06:04 min • September 2nd, 2020
September 2nd, 2020 •
1,2, 1, 1,2
1Laboratory of Clinical Pharmacy and Pharmacology, Musashino University, 2Research Institute of Pharmaceutical Sciences, Musashino University

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Den forbigående receptor potentielle vanilloid type 1 (TRPV1) i supraspinal regionen er blevet foreslået at spille nogle roller i hjernefunktionen. Beskrevet her er en protokol for intracerebroventricular injektion af harpiksiiferatoxin for supraspinal TRPV1 desensibilisering i mus. Procedurer for nogle smerte test er også præsenteret.

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Neurovidenskab Problem 163 forbigående receptor potentiel vanilloid type 1 (TRPV1) resiniferatoxin intracerebroventricular injektion nociception RTX test haletryk test acetaminophen
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