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Caracterização da ruptura de membrana de Plasma MLKL-mediada em Necroptosis

Article DOI: 10.3791/58088-v • 08:55 min • August 7th, 2018
August 7th, 2018 •
*1,2, *3, 3, 3, 1,2
1Department of Structural Biology, St. Jude Children's Research Hospital, 2Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 3Department of Immunology, St. Jude Children's Research Hospital
* These authors contributed equally

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Nós relatamos métodos para a caracterização da ruptura de membrana de plasma MLKL-mediada em necroptosis incluindo imagem de microscopia de viver-pilha convencional e confocal, varredura microscopia eletrônica e vinculação de lipídios NMR-baseado.

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Biologia edição 138 Necroptosis misturado a linhagem domínio como kinased (MLKL) permeabilização da membrana plasmática viver-pilha microscopia microscopia eletrônica espectroscopia RMN remodelamento
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