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JoVE Journal Neuroscience
A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
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A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Article DOI: 10.3791/63951-v • 06:54 min • June 22nd, 2022
June 22nd, 2022 •
*1, *1, 1, 2, 1
1Department of Neuroscience, UConn School of Medicine, 2Division of Neurosurgery, UConn School of Medicine
* These authors contributed equally

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The protocol aims to provide methods for encephalomyosynangiosis-grafting of a vascular temporalis muscle flap on the pial surface of ischemic brain tissue-for the treatment of non-moyamoya acute ischemic stroke. The approach's efficacy in increasing angiogenesis is evaluated using a transient middle cerebral artery occlusion model in mice.

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Middle Cerebral Artery Occlusion Stroke Mice Vascular Network Stroke Recovery EMS Surgery Angiogenesis Blood Flow Ischemic Tissue Pharmacological Interventions Therapeutic Potential Hemicraniectomy Prompt Stroke Recovery Neuroangiogenesis Neurogenesis Rodent Surgery Sterilize Instruments Autoclaving Sanitize Operating Surface Anesthesia Toe Pinching Ophthalmic Ointment
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