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Édition de base efficace sans PAM pour la modélisation des maladies génétiques humaines chez le poisson zèbre avec zSpRY-ABE8e
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Édition de base efficace sans PAM pour la modélisation des maladies génétiques humaines chez le poisson zèbre avec zSpRY-ABE8e

Article DOI: 10.3791/64977-v • 07:31 min • February 17th, 2023
February 17th, 2023 •
1,2, 3, 1,2, 4, 1,2, 1,2
1Key Laboratory of Brain, Cognition and Education Science, Ministry of Education, 2Institute for Brain Research and Rehabilitation, Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, 3Institute of Modern Aquaculture Science and Engineering, Guangdong Provincial Engineering Technology Research Center for Environmentally Friendly Aquaculture, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences, South China Normal University, 4Department of Pathology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences

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Ce protocole décrit comment effectuer une édition efficace de la base d’adénine sans limitation PAM pour construire un modèle précis de maladie du poisson zèbre en utilisant zSpRY-ABE8e.

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