Hyungshin Yim College of Pharmacy and Institute of Pharmaceutical Science and Technology Hanyang University Biography Publications Institution JoVE Articles Hyungshin Yim has not added a biography. If you are Hyungshin Yim and would like to personalize this page please email our Author Liaison for assistance. Publications Comparative Analysis of a FRET-based PLK1 Kinase Assay to Identify PLK1 Inhibitors for Chemotherapy Anticancer Research. 03, 2017 | Pubmed ID: 28314279 Roles of SALL2 in Tumorigenesis Archives of Pharmacal Research. Feb, 2017 | Pubmed ID: 27957650 Sensitivity of TP53-Mutated Cancer Cells to the Phytoestrogen Genistein Is Associated With Direct Inhibition of Plk1 Activity Journal of Cellular Physiology. Nov, 2016 | Pubmed ID: 27861885 Antiinflammatory and Analgesic Effects of Eurycoma Longifolia Extracts Archives of Pharmacal Research. Mar, 2016 | Pubmed ID: 26832325 Differential Cellular Effects of Plk1 Inhibitors Targeting the ATP-binding Domain or Polo-box Domain Journal of Cellular Physiology. Dec, 2015 | Pubmed ID: 25975351 The Tumor Suppressor Protein P150(Sal2) in Carcinogenesis Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. Feb, 2015 | Pubmed ID: 25608837 A Mouse Polyomavirus-encoded MicroRNA Targets the Cellular Apoptosis Pathway Through Smad2 Inhibition Virology. Nov, 2014 | Pubmed ID: 25146733 Predictive Value of Urinary and Serum Biomarkers in Young Children with Febrile Urinary Tract Infections Pediatric Nephrology (Berlin, Germany). Nov, 2014 | Pubmed ID: 24924751 Plk1-targeted Therapies in TP53- or RAS-mutated Cancer Mutation Research. Reviews in Mutation Research. Mar, 2014 | Pubmed ID: 24630986 ATM Kinase Promotes Both Caspase-8 and Caspase-9 Activation During TNF-α-induced Apoptosis of HeLa Cells FEBS Letters. Mar, 2014 | Pubmed ID: 24530529 Synergistic Effect of Simvastatin Plus NS398 on Inhibition of Proliferation and Survival in Hepatocellular Carcinoma Cell Line Journal of Gastroenterology and Hepatology. Jun, 2014 | Pubmed ID: 24372723 Two Nuclear Export Signals of Cdc6 Are Differentially Associated with CDK-mediated Phosphorylation Residues for Cytoplasmic Translocation Biochimica Et Biophysica Acta. Feb, 2014 | Pubmed ID: 24216307 Current Clinical Trials with Polo-like Kinase 1 Inhibitors in Solid Tumors Anti-cancer Drugs. Nov, 2013 | Pubmed ID: 23949254 The Accumulation of DNA Repair Defects is the Molecular Origin of Carcinogenesis Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. Dec, 2013 | Pubmed ID: 23907577 Phosphorylation of Cdc6 at Serine 74, but Not at Serine 106, Drives Translocation of Cdc6 to the Cytoplasm Journal of Cellular Physiology. Jun, 2013 | Pubmed ID: 23129444 The Polyoma Virus Large T Binding Protein P150 is a Transcriptional Repressor of C-MYC PloS One. 2012 | Pubmed ID: 23029531 Cdk2 Acts Upstream of Mitochondrial Permeability Transition During Paclitaxel-induced Apoptosis Protein & Cell. Jul, 2011 | Pubmed ID: 21822799 Regulation of the Final Stage of Mitosis by Components of the Pre-replicative Complex and a Polo Kinase Cell Cycle (Georgetown, Tex.). May, 2011 | Pubmed ID: 21519187 Nek1 and TAZ Interact to Maintain Normal Levels of Polycystin 2 Journal of the American Society of Nephrology : JASN. May, 2011 | Pubmed ID: 21474562 DNA-binding and Regulatory Properties of the Transcription Factor and Putative Tumor Suppressor P150(Sal2) Biochimica Et Biophysica Acta. Apr-Jun, 2011 | Pubmed ID: 21362508 Transcriptional and Post-translational Regulation of the Quiescence Factor and Putative Tumor Suppressor P150(Sal2) FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Apr, 2011 | Pubmed ID: 21228219 Cell Division Cycle 6, a Mitotic Substrate of Polo-like Kinase 1, Regulates Chromosomal Segregation Mediated by Cyclin-dependent Kinase 1 and Separase Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010 | Pubmed ID: 21041660 Polo-like Kinase 1 Depletion Induces DNA Damage in Early S Prior to Caspase Activation Molecular and Cellular Biology. May, 2009 | Pubmed ID: 19289504 ATR (AT Mutated Rad3 Related) Activity Stabilizes Cdc6 and Delays G2/M-phase Entry During Hydroxyurea-induced S-phase Arrest of HeLa Cells The International Journal of Biochemistry & Cell Biology. Jun, 2009 | Pubmed ID: 19154794 Cyclin-dependent Protein Kinase 2 Activity is Required for Mitochondrial Translocation of Bax and Disruption of Mitochondrial Transmembrane Potential During Etoposide-induced Apoptosis Apoptosis : an International Journal on Programmed Cell Death. Jul, 2007 | Pubmed ID: 17252195 Ginsenoside-Rh2-induced Mitochondrial Depolarization and Apoptosis Are Associated with Reactive Oxygen Species- and Ca2+-mediated C-Jun NH2-terminal Kinase 1 Activation in HeLa Cells The Journal of Pharmacology and Experimental Therapeutics. Dec, 2006 | Pubmed ID: 16973888 Cleavage of Cdc6 by Caspase-3 Promotes ATM/ATR Kinase-mediated Apoptosis of HeLa Cells The Journal of Cell Biology. Jul, 2006 | Pubmed ID: 16801388 Caspase-3-mediated Cleavage of Cdc6 Induces Nuclear Localization of P49-truncated Cdc6 and Apoptosis Molecular Biology of the Cell. Oct, 2003 | Pubmed ID: 14517333 Cdk2 Activity is Associated with Depolarization of Mitochondrial Membrane Potential During Apoptosis Biochemical and Biophysical Research Communications. Jun, 2003 | Pubmed ID: 12767926 Oligopeptide Competition Assay for Phosphorylation Site Determination Min Sung Joo1, Ja Hyun Koo1, Sol-Bi Shin2, Hyungshin Yim2, Sang Geon Kim1 1College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 2College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University JoVE 55708 Biochimie
Oligopeptide Competition Assay for Phosphorylation Site Determination Min Sung Joo1, Ja Hyun Koo1, Sol-Bi Shin2, Hyungshin Yim2, Sang Geon Kim1 1College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, 2College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University JoVE 55708 Biochimie