Vadim Cherezov The Bridge Institute University of Southern California Biography Publications Institution JoVE Articles Vadim Cherezov has not added a biography. If you are Vadim Cherezov and would like to personalize this page please email our Author Liaison for assistance. Publications Serial Femtosecond Crystallography of Membrane Proteins Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 27553241 Serial Femtosecond Crystallography Datasets from G Protein-coupled Receptors Scientific Data. 2016 | Pubmed ID: 27479354 X-ray Laser Diffraction for Structure Determination of the Rhodopsin-arrestin Complex Scientific Data. 2016 | Pubmed ID: 27070998 The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR-Ligand Interactions Journal of Chemical Information and Modeling. Jan, 2016 | Pubmed ID: 26642258 Serial Femtosecond X-ray Diffraction of Enveloped Virus Microcrystals Structural Dynamics (Melville, N.Y.). Jul, 2015 | Pubmed ID: 26798819 Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase Nature Communications. 2015 | Pubmed ID: 26673816 The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor Structure (London, England : 1993). Dec, 2015 | Pubmed ID: 26526853 Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor The Journal of Biological Chemistry. Dec, 2015 | Pubmed ID: 26420482 Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase IUCrJ. Sep, 2015 | Pubmed ID: 26306196 Crystal Structure of Rhodopsin Bound to Arrestin by Femtosecond X-ray Laser Nature. Jul, 2015 | Pubmed ID: 26200343 A Novel Inert Crystal Delivery Medium for Serial Femtosecond Crystallography IUCrJ. Jul, 2015 | Pubmed ID: 26177184 Fluorescence Recovery After Photobleaching in Lipidic Cubic Phase (LCP-FRAP): A Precrystallization Assay for Membrane Proteins Methods in Enzymology. 2015 | Pubmed ID: 25950976 Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography Cell. May, 2015 | Pubmed ID: 25913193 Lipidic Cubic Phase Serial Millisecond Crystallography Using Synchrotron Radiation IUCrJ. Mar, 2015 | Pubmed ID: 25866654 Two Disparate Ligand-binding Sites in the Human P2Y1 Receptor Nature. Apr, 2015 | Pubmed ID: 25822790 GPCR Structure, Function, Drug Discovery and Crystallography: Report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014 Naunyn-Schmiedeberg's Archives of Pharmacology. Aug, 2015 | Pubmed ID: 25772061 Structural Basis for Bifunctional Peptide Recognition at Human δ-opioid Receptor Nature Structural & Molecular Biology. Mar, 2015 | Pubmed ID: 25686086 Structural Biology. Crystal Structure of the Chemokine Receptor CXCR4 in Complex with a Viral Chemokine Science (New York, N.Y.). Mar, 2015 | Pubmed ID: 25612609 Generic GPCR Residue Numbers - Aligning Topology Maps While Minding the Gaps Trends in Pharmacological Sciences. Jan, 2015 | Pubmed ID: 25541108 Two Classes of Cholesterol Binding Sites for the β2AR Revealed by Thermostability and NMR Biophysical Journal. Nov, 2014 | Pubmed ID: 25418299 Constitutive Phospholipid Scramblase Activity of a G Protein-coupled Receptor Nature Communications. 2014 | Pubmed ID: 25296113 Preparation of Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography Nature Protocols. Sep, 2014 | Pubmed ID: 25122522 Structural Basis for Smoothened Receptor Modulation and Chemoresistance to Anticancer Drugs Nature Communications. 2014 | Pubmed ID: 25008467 Femtosecond Crystallography of Membrane Proteins in the Lipidic Cubic Phase Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. Jul, 2014 | Pubmed ID: 24914147 Agonist-bound Structure of the Human P2Y12 Receptor Nature. May, 2014 | Pubmed ID: 24784220 Allosteric Sodium in Class A GPCR Signaling Trends in Biochemical Sciences. May, 2014 | Pubmed ID: 24767681 Structure of the Human P2Y12 Receptor in Complex with an Antithrombotic Drug Nature. May, 2014 | Pubmed ID: 24670650 Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator Science (New York, N.Y.). Apr, 2014 | Pubmed ID: 24603153 Lipidic Cubic Phase Injector Facilitates Membrane Protein Serial Femtosecond Crystallography Nature Communications. 2014 | Pubmed ID: 24525480 Molecular Control of δ-opioid Receptor Signalling Nature. Feb, 2014 | Pubmed ID: 24413399 Functional Assay for T4 Lysozyme-engineered G Protein-coupled Receptors with an Ion Channel Reporter Structure (London, England : 1993). Jan, 2014 | Pubmed ID: 24268646 Serial Femtosecond Crystallography of G Protein-coupled Receptors Science (New York, N.Y.). Dec, 2013 | Pubmed ID: 24357322 The Role of a Sodium Ion Binding Site in the Allosteric Modulation of the A(2A) Adenosine G Protein-coupled Receptor Structure (London, England : 1993). Dec, 2013 | Pubmed ID: 24210756 Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex Science (New York, N.Y.). Sep, 2013 | Pubmed ID: 24030490 Structure-based Ligand Discovery Targeting Orthosteric and Allosteric Pockets of Dopamine Receptors Molecular Pharmacology. Dec, 2013 | Pubmed ID: 24021214 Structure of the Human Glucagon Class B G-protein-coupled Receptor Nature. Jul, 2013 | Pubmed ID: 23863937 Integrated Nonlinear Optical Imaging Microscope for On-axis Crystal Detection and Centering at a Synchrotron Beamline Journal of Synchrotron Radiation. Jul, 2013 | Pubmed ID: 23765294 Hydrogen Bonding of Cholesterol in the Lipidic Cubic Phase Langmuir : the ACS Journal of Surfaces and Colloids. Jun, 2013 | Pubmed ID: 23763339 Structure of the Human Smoothened Receptor Bound to an Antitumour Agent Nature. May, 2013 | Pubmed ID: 23636324 Towards Protein-crystal Centering Using Second-harmonic Generation (SHG) Microscopy Acta Crystallographica. Section D, Biological Crystallography. May, 2013 | Pubmed ID: 23633594 Structural Features for Functional Selectivity at Serotonin Receptors Science (New York, N.Y.). May, 2013 | Pubmed ID: 23519215 Structural Basis for Molecular Recognition at Serotonin Receptors Science (New York, N.Y.). May, 2013 | Pubmed ID: 23519210 The GPCR Network: a Large-scale Collaboration to Determine Human GPCR Structure and Function Nature Reviews. Drug Discovery. Jan, 2013 | Pubmed ID: 23237917 Structure-function of the G Protein-coupled Receptor Superfamily Annual Review of Pharmacology and Toxicology. 2013 | Pubmed ID: 23140243 Kristallstruktur Eines Voltage-gated K + Kanal Pore Moduls Im Geschlossenen Zustand in Lipidmembranen The Journal of Biological Chemistry. Dec, 2012 | Pubmed ID: 23095758 Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions Science (New York, N.Y.). Jul, 2012 | Pubmed ID: 22798613 Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-coupled Receptors Structure (London, England : 1993). Jun, 2012 | Pubmed ID: 22681902 Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. Coli and Enteropathogenic Y. Pseudotuberculosis Structure (London, England : 1993). Jul, 2012 | Pubmed ID: 22658748 Structure of the Nociceptin/orphanin FQ Receptor in Complex with a Peptide Mimetic Nature. 2012 | Pubmed ID: 22596163 Structure of the Human κ-opioid Receptor in Complex with JDTic Nature. May, 2012 | Pubmed ID: 22437504 Vielfalt Und Modularität Von G-Protein-gekoppelter Rezeptor-Strukturen Trends in Pharmacological Sciences. Jan, 2012 | Pubmed ID: 22032986 GPCR Stabilisierung Verwendet Die Bicelle-ähnliche Architektur Von Gemischten Sterin-Waschmittel-Mizellen Methods (San Diego, Calif.). Dec, 2011 | Pubmed ID: 22041719 Charakterisierung Der Lipid-Matrizen Für Membrane Proteinkristallisation Von Hochdurchsatz-kleine Winkel Röntgenstreuung Methods (San Diego, Calif.). Dec, 2011 | Pubmed ID: 21903166 Hochauflösende Struktur Der Ba3 Cytochrom-C-Oxidase Aus Thermus Thermophilus in Einer Lipidischen Umgebung PloS One. 2011 | Pubmed ID: 21814577 Lipidischen Kubische Phase Technologien Für Membrane Protein Strukturelle Studien Current Opinion in Structural Biology. Aug, 2011 | Pubmed ID: 21775127 Struktur Der Menschlichen Histamin H1-Rezeptor-Komplex Mit Doxepin Nature. Jul, 2011 | Pubmed ID: 21697825 Entwicklung Eines Automatisierten Hochdurchsatz-LCP-FRAP-Tests-Guide Membran Proteinkristallisation in Lipid Mesophasen Crystal Growth & Design. Apr, 2011 | Pubmed ID: 21660116 Struktur Ein Agonist Gebundene Menschliche A2A Adenosin-Rezeptor Science (New York, N.Y.). Apr, 2011 | Pubmed ID: 21393508 Struktur Des Menschlichen Dopamin D3-Rezeptors Im Komplex Mit Einem Selektiven D2/D3-Antagonist Science (New York, N.Y.). Nov, 2010 | Pubmed ID: 21097933 Strukturen Der Chemokine CXCR4 GPCR, Mit Klein-Molekül Und Zyklische Peptid-Antagonisten Science (New York, N.Y.). Nov, 2010 | Pubmed ID: 20929726 Konservierte Bindungsmodus Menschlichen Beta2-adrenerge Rezeptor-inverse Agonisten Und Antagonisten Durch Kristallstrukturanalyse Aufgedeckt Journal of the American Chemical Society. Aug, 2010 | Pubmed ID: 20669948 Jüngste Fortschritte Bei Der Struktur-Bestimmung Der GPCRs, Eine Membran-Protein-Familie Mit Hohem Potenzial Als Pharmazeutische Ziele Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20665265 LCP-Tm: Eine Probe Zu Messen Und Stabilität Von Membranproteinen in Einer Membran-Umgebung Zu Verstehen Biophysical Journal. Apr, 2010 | Pubmed ID: 20409473 Nichtlineare Optische Bildgebung Von Integralen Membrane Protein-Kristallen in Lipidischen Mesophasen Analytical Chemistry. Jan, 2010 | Pubmed ID: 20025250 Rastering Strategie Für Screening Und Zentrierung Von Microcrystal Proben Menschlichen Membranproteine Mit Einer Sub-10 Microm Größe Synchrotron Röntgenstrahl Journal of the Royal Society, Interface / the Royal Society. Oct, 2009 | Pubmed ID: 19535414 Membranproteine Mit Lipidischen Mesophasen Kristallisieren Nature Protocols. 2009 | Pubmed ID: 19390528 Analyse Der Vollständige Und Partielle Agonisten an Beta2-adrenerge Rezeptor Binden Schlägt Eine Rolle Der Transmembran-Helix V in Agonist-spezifische Konformationsveränderungen Journal of Molecular Recognition : JMR. Jul-Aug, 2009 | Pubmed ID: 19353579 LCP-FRAP Assay Für Inlandflügen Membranproteinen Für in Meso-Kristallisation Crystal Growth & Design. 2008 | Pubmed ID: 19234616 Die 2,6 Ångström-Kristallstruktur Einer Menschlichen A2A Adenosin-Rezeptor an Ein Antagonist Gebunden Science (New York, N.Y.). Nov, 2008 | Pubmed ID: 18832607 Einblicke in Die Wirkungsweise Des Vermeintlichen Zink Transporter CzrB in Thermus Thermophilus Structure (London, England : 1993). Sep, 2008 | Pubmed ID: 18786400 Eine Bestimmte Cholesterin-Bindungsstelle Wird Durch Die 2,8 A-Struktur Der Menschlichen Beta2-adrenerge Rezeptor Eingerichtet Structure (London, England : 1993). Jun, 2008 | Pubmed ID: 18547522 Schlagen Sie in Meso-Kristall Struktur Und Docking-Simulationen Eine Alternative Proteoglycan-Bindungsstelle in Der OpcA Außenmembran Adhesin Proteins. Apr, 2008 | Pubmed ID: 18076035 Hochauflösende Kristallstruktur Ein Veränderter Mensch Beta2-adrenerge G Protein-gekoppelter Rezeptor Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 17962520 GPCR-Technik Liefert Hochauflösende Strukturelle Einblicke in Beta2-adrenerge Rezeptor-Funktion Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 17962519 Membran Proteinkristallisation in Lipidischen Mesophasen. Ein Mechanismus Studienwoche Röntgen-Microdiffraction Faraday Discussions. 2007 | Pubmed ID: 17955811 Kristallisation Und Vorläufige Röntgenbeugung Analyse Eines Löslichen Domains Der Die Vermeintliche Zink-Transporter CzrB Aus Thermus Thermophilus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Aug, 2007 | Pubmed ID: 17671365 Steuern Den Durchgang Von Licht Durch Metall Mikrokanälen Durch Nanocoatings Von Phospholipiden The Journal of Physical Chemistry. B. Nov, 2006 | Pubmed ID: 17064131 Molekulare Organisation Des Cholesterins Im Ungesättigten Phosphatidylethanolamines: Röntgenbeugung Und Solid-State-2 H-NMR Zeigen Unterschiede Mit Phosphatidylcholines Journal of the American Chemical Society. Apr, 2006 | Pubmed ID: 16620109 Raum Zu Bewegen: Kristallisieren Membranproteinen in Geschwollene Lipidischen Mesophasen Journal of Molecular Biology. Apr, 2006 | Pubmed ID: 16490208 Membrane Protein Kristallisation in Lipid-Doppelschichten Mit Maßgeschneiderten Mesophasen Structure (London, England : 1993). Dec, 2004 | Pubmed ID: 15576026 Ordnung Aus Unordnung, Einsperrend Cholesterin Mit Chaotischen Lipiden. Die Rolle Von Mehrfach Ungesättigten Lipiden in Membranfloß Bildung Chemistry and Physics of Lipids. Nov, 2004 | Pubmed ID: 15530450 Rationales Design Von Lipid-Membran Für Protein Kristallisation Journal of Structural Biology. Nov, 2004 | Pubmed ID: 15477097 Ein Robotersystem Für Die Kristallisation Von Membran Und Lösliche Proteine in Lipid-Mesophasen Acta Crystallographica. Section D, Biological Crystallography. Oct, 2004 | Pubmed ID: 15388926 Interaktion Von Cholesterin Mit Einem Docosahexaensäure Enthaltenden Phosphatidylethanolamin: Auslöser Für Mikrodomäne / Floß Bildung? Biochemistry. Oct, 2003 | Pubmed ID: 14556634 Membrane Protein Kristallisation in Meso: Lipid-Typ-Schneiderei Der Kubischen Phase Biophysical Journal. Dec, 2002 | Pubmed ID: 12496106 Too Hot to Handle? Synchrotron-Röntgen-Schaden Von Lipidmembranen Und Mesophasen Journal of Synchrotron Radiation. Nov, 2002 | Pubmed ID: 12409619 Kontrollierende Membran Cholesteringehalt. Eine Rolle Für Die Mehrfach Ungesättigten (Docosahexaenoat) Phospholipide Biochemistry. Oct, 2002 | Pubmed ID: 12369842 Biophysikalische Und Transfektionsstudien Der DIC (14) -amidine/DNA Komplex Biophysical Journal. Jun, 2002 | Pubmed ID: 12023234 Molekulare Organisation Von Cholesterin in Membranen Mehrfach Ungesättigte: Mikrodomänenbildung Biophysical Journal. Jan, 2002 | Pubmed ID: 11751316 Herstellung und Lieferung von Protein Microcrystals in Lipidische Cubic Phase für Serial Femtosekunden Kristallographie Andrii Ishchenko1,2, Vadim Cherezov1,2, Wei Liu3 1The Bridge Institute, University of Southern California, 2Department of Chemistry, University of Southern California, 3School of Molecular Sciences, Center for Applied Structural Discovery at the Biodesign Institute, Arizona State University Biochimie Die Kristallisation von Membranproteinen in Lipidische Mesophasen Wei Liu1, Vadim Cherezov1 1Molecular Biology, The Scripps Research Institute JoVE 2501 Biologie
Herstellung und Lieferung von Protein Microcrystals in Lipidische Cubic Phase für Serial Femtosekunden Kristallographie Andrii Ishchenko1,2, Vadim Cherezov1,2, Wei Liu3 1The Bridge Institute, University of Southern California, 2Department of Chemistry, University of Southern California, 3School of Molecular Sciences, Center for Applied Structural Discovery at the Biodesign Institute, Arizona State University Biochimie
Die Kristallisation von Membranproteinen in Lipidische Mesophasen Wei Liu1, Vadim Cherezov1 1Molecular Biology, The Scripps Research Institute JoVE 2501 Biologie