Dominant Follicle Selection
Dominant Follicle Selection - Related Videos
01:29
Dominant and Dominated Strategies
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2025
In strategic decision-making, a dominant strategy is one that always provides the best outcome for a player, no matter what the other players decide. This ensures that the player's payoff is maximized regardless of the choices made by others. On the other hand, a dominated strategy consistently leads to a worse outcome than another available strategy, regardless of the opponent's decision. For instance, imagine two firms competing in a market by setting production levels—either high or low.
08:44
The Utility of Stage-specific Mid-to-late Drosophila Follicle Isolation
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Cited by 12 •
2013
Stage-specific isolation of mid-to-late Drosophila follicles is useful for a variety of purposes. Such follicles develop in culture, which allows for genetic and/or pharmacologic manipulations to be coupled with in vitro development assays and live imaging. Additionally, follicles can be used for molecular studies, such as isolating mRNA and protein.
10:31
Application of a Novel Hyaluronan Hydrogel for Three-Dimensional Follicle Culture and Methodology for Mouse Ovarian Follicle Cryopreservation
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Cited by 2 •
2025
This protocol describes a novel three-dimensional (3-D) culture model using a tyramine-linked hyaluronan hydrogel to encapsulate and culture preantral follicles from the mouse ovary. We also detail two approaches to ovarian follicle cryopreservation by vitrification.
01:43
Incomplete Dominance
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2021
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism. According to Mendel, organisms with both copies or a single copy of the dominant allele display a...
10:41
Culture and Co-Culture of Mouse Ovaries and Ovarian Follicles
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Cited by 16 •
2015
This protocol describes the primary culture/co-culture of mouse ovarian tissue, using ovaries from neonatal mice and individual ovarian follicles from prepubertal mice. The culture techniques support development in a highly physiological manner, allowing investigation of the effect of extrinsic agents on the ovary, and of interactions between ovarian follicles.
FAQs
Selection depends on relative FSH sensitivity within the developing cohort. While FSH is available, multiple follicles can grow; as FSH levels decline, the follicle able to respond effectively continues development. Follicles with lower effective sensitivity lose support and are more likely to undergo atresia, making differential hormone responsiveness the key mechanism behind developmental priority.
The developing priority follicle produces estradiol and inhibin, which contribute to further suppression of FSH. This creates a reinforcing feedback pattern: reduced FSH support disadvantages competing follicles, while the more FSH-sensitive follicle continues growing. The interaction links ovarian follicle development with endocrine regulation and helps narrow a broad cohort toward a single likely ovulatory follicle.
Its outcome is not limited to growth of one follicle. As FSH declines, competing follicles are more likely to enter atresia, while the selected follicle retains developmental support. This coordination usually favors release of one oocyte and helps regulate the number of oocytes available for ovulation, connecting follicular competition with reproductive timing.
The process is especially relevant during the follicular phase, when a cohort responds to FSH and differences in responsiveness become consequential. Its timing allows follicle growth, changing FSH conditions, and ovarian hormone feedback to be coordinated before ovulation. Understanding this sequence helps explain how ovarian activity is organized within the menstrual cycle rather than occurring as independent follicle growth.
In biology, studying dominant follicle selection provides a framework for interpreting ovarian physiology and menstrual-cycle regulation. It also clarifies how reproductive timing is coordinated and why follicle competition affects the number of oocytes released. These connections make the process useful for relating follicle behavior to whole-organ reproductive outcomes.
The process is relevant because fertility depends on coordinated follicle development, ovulation, and reproductive timing. Its study helps researchers interpret how ovarian follicles respond when reproductive function is altered or when assisted reproductive treatments influence follicle development. It also provides context for multiple ovulation, where the relationship between follicle competition and the number of oocytes released becomes especially important.