Follicle Stimulating Hormone Testosterone

Follicle-stimulating hormone (FSH) and testosterone are reproductive hormones that coordinate gamete production, sexual development, and fertility in the hypothalamic-pituitary-gonadal axis. The pituitary releases FSH, which acts on ovarian follicles and testicular Sertoli cells, while luteinizing hormone stimulates Leydig cells to produce testosterone; these hormones then regulate reproductive tissues and feed back to the brain and pituitary to control hormone release. Studying their interactions helps explain puberty, menstrual and spermatogenic function, and hormone-related infertility. Clinical measurement and hormone-based treatments also support the evaluation and management of reproductive and endocrine disorders.

Follicle Stimulating Hormone Testosterone - Related Videos

Education

JoVE Core - Biology

Types of Hormones

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2019

Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells. Steroid hormones are derived from cholesterol and are lipophilic in nature. This allows them to readily traverse the lipid-rich cell membrane to bind to their intracellular receptors in the cytoplasm or nucleus. Once bound, the cytoplasmic hormone-receptor complex translocates to the nucleus.

Research

JoVE Journal - Biology
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Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model

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2023

Follicle-stimulating hormone (FSH) in various extragonadal tissues and organs is associated with the pathogenesis of multiple diseases. The ovariectomized and FSH-treated mouse model (OVF) can be used to explore the extragonadal actions of FSH.

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

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Cited by 9 •

2011

The procedure described in this protocol shows that testosterone administration and folk beliefs about testosterone may be associated with directly opposed social behaviors.

Combined Recording of Mechanically Stimulated Afferent Output and Nerve Terminal Labelling in Mouse Hair Follicles

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2025

This video demonstrates the combined recording of mechanically stimulated afferent output and nerve terminal labeling in the hair follicles of a mouse pinna. It outlines the steps involved in the mechanical stimulation of hair follicle nerve terminals before and after exposure to a fluorescent membrane dye, electrophysiology recording of the generated action potentials, and visualization of the nerve terminal labeling in the hair follicles.

Culture and Co-Culture of Mouse Ovaries and Ovarian Follicles

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Cited by 16 •

2015

This protocol describes the primary culture/co-culture of mouse ovarian tissue, using ovaries from neonatal mice and individual ovarian follicles from prepubertal mice. The culture techniques support development in a highly physiological manner, allowing investigation of the effect of extrinsic agents on the ovary, and of interactions between ovarian follicles.

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