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Oral Submucous Fibrosis Tissue Sample Preparation for Hematoxylin-Eosin Staining (Video) | JoVE

Capturing Oral Submucous Fibrosis Tissue Samples for Spatial-Omics Analysis

Article DOI: 10.3791/200508-v • 02:14 min • August 11th, 2023
August 11th, 2023 •
1,2, 3, 1,2, 1,2
1Department of Oral Pathology, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, 2Research Unit of Precision Pathologic Diagnosis in Tumors of the Oral and Maxillofacial Regions, Chinese Academy of Medical Sciences (2019RU034), 3Central Laboratory, Peking University School and Hospital of Stomatology

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Isolierung Zellen morphologische Informationen räumliche Informationen orale submuköse Fibroseproben Laser-Capture-Mikrodissektion potentiell maligne Erkrankung Atrophie Epithel Fibrose Lamina propria Submukosa histopathologische Objektträger Epitheldysplasie seneszente Fibroblasten maligne Transformation molekulare Mechanismen Heterogenität orales Plattenepithelkarzinom spezifische molekulare Mechanismen Formalinfixierte Paraffin-eingebettete Gewebeobjektträger Mikroskop mikroskalige Dysplastik Gewebe atrophisches Epithelgewebe fibrotisches subepitheliales Gewebe Genomsequenzierung Transkriptomsequenzierung Genomdaten Transkriptomdaten
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