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Immunhistochemische Färbung von B7-H1 (PD-L1) auf Paraffin-embedded Slides der Pankreaskarzinom Tissue
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Immunhistochemische Färbung von B7-H1 (PD-L1) auf Paraffin-embedded Slides der Pankreaskarzinom Tissue

Article DOI: 10.3791/4059-v • 10:11 min • January 3rd, 2013
January 3rd, 2013 •
1,2, 1,2, 1,2,3, 1, 1,2,4, 3,5, 6, 1,2,5,7,8, 1,2,5,8, 1,2,4,5,7
1The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 2Department of Oncology, The Johns Hopkins University School of Medicine, 3Department of Dermatology, The Johns Hopkins University School of Medicine, 4Department of Surgery, Johns Hopkins University School of Medicine, 5The Sol Goldman Pancreatic Cancer Center, The Johns Hopkins University School of Medicine, 6Yale Cancer Center, Yale School of Medicine, 7The Skip Viragh Center for Pancreatic Cancer, The Johns Hopkins University School of Medicine, 8Department of Pathology, The Johns Hopkins University School of Medicine

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B7-H1 (PD-L1) und seine Bindung an PD-1 einen großen tumorinduzierte immunsuppressiven Signal in Mikroumgebung des Tumors. Eine immunhistochemische Färbetechnik, die Expression und Lokalisation von B7-H1 in Pankreaskarzinom zu charakterisieren ist hier beschrieben.

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Cancer Biology Ausgabe 71 Medizin Immunologie Biochemie Molekularbiologie Zellbiologie Chemie Onkologie Immunhistochemie B7-H1 (PD-L1) Pankreaskarzinom Bauchspeicheldrüsenkrebs Pankreas- Tumor- T-Zell-Immunität Krebs
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