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Journal / Bioengineering / 高通量自动 Microbioreactor 系统在 CHO 细胞模型 IgG1…
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Bioengineering

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JoVE Journal Bioengineering
高通量自动 Microbioreactor 系统在 CHO 细胞模型 IgG1 生产中的应用
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高通量自动 Microbioreactor 系统在 CHO 细胞模型 IgG1 生产中的应用

Article DOI: 10.3791/58231-v • 08:15 min • September 28th, 2018
September 28th, 2018 •
1, 1, 1, 1, 1, 1, 1, 1, 1
1Center for Drug Evaluation and Research, Office of Product Quality, Office of Biotechnology Products, Division of Biotechnology Review and Research II, U.S. Food and Drug Administration

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提出了一种 microbioreactor 系统在不同条件下并行运行48平行细胞培养的详细协议。介绍了细胞培养过程、收获和随后的抗体效价分析。

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生物工程 139 期 微生物反应器 中国仓鼠卵巢细胞 细胞培养 筛查 多糖 单克隆抗体 大小排斥色谱 多角度光散射。
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