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Journal / Genetics / Kartlägga Alzheimers sjukdom varianter till sina…
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Genetics

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JoVE Journal Genetics
Kartlägga Alzheimers sjukdom varianter till sina målgener med hjälp av Computational analys av kromatin konfiguration
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Kartlägga Alzheimers sjukdom varianter till sina målgener med hjälp av Computational analys av kromatin konfiguration

Article DOI: 10.3791/60428-v • 04:41 min • January 9th, 2020
January 9th, 2020 •
1,2, 3, *3,4, *1,2
1Department of Genetics, University of North Carolina, 2Neuroscience Center, University of North Carolina, 3Thurston Arthritis Research Center, University of North Carolina, 4Department of Cell Biology and Physiology, University of North Carolina
* These authors contributed equally

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Vi presenterar ett protokoll för att identifiera funktionella implikationer av icke-kodningsvarianter identifierade genom genomomfattande Associations studier (GWAS) med hjälp av tredimensionella kromatininteraktioner.

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Genetik fråga 155 Hi-C GWAS icke-kodning varianter Genkartläggning funktionsgenomik Alzheimers sjukdom
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