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Immunology and Infection

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JoVE Journal Immunology and Infection
Bakteriyel Keratite Karşı İlaç Tedavilerini İncelemek İçin Porcine Ex Vivo Kornea Modeli Kurulması
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Bakteriyel Keratite Karşı İlaç Tedavilerini İncelemek İçin Porcine Ex Vivo Kornea Modeli Kurulması

Article DOI: 10.3791/61156-v • 09:22 min • May 12th, 2020
May 12th, 2020 •
1,2, 3, 4, 1,5, 3, 1,6, 1,7, 1,2
1Sheffield Collaboratorium for Antimicrobial Resistance and Biofilms (SCARAB), University of Sheffield, 2Department of Chemical and Biological Engineering, University of Sheffield, 3Hyderabad Eye Research Foundation, L V Prasad Eye Institute, 4Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, 5Department of Molecular Biology and Biotechnology, University of Sheffield, 6Department of Materials Science and Engineering, University of Sheffield, 7Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield

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Bu makalede, bakteriyel keratitin ex vivo porcine modelini kurmak için adım adım bir protokol açıklanmaktadır. Pseudomonas aeruginosa prototipik bir organizma olarak kullanılır. Bu yenilikçi model in vivo enfeksiyonu taklit eder, çünkü bakteri çoğalması bakterinin kornea dokusuna zarar verme yeteneğine bağlıdır.

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İmmünoloji ve Enfeksiyon Sayı 159 Pseudomonas aeruginosa keratit kornea ex vivo göz porcine
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