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En gnavermodel af Ross-operationen
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En gnavermodel af Ross-operationen: Syngeneisk lungearterietransplantatimplantation i en systemisk position

Article DOI: 10.3791/63179-v • 11:20 min • April 1st, 2022
April 1st, 2022 •
*1, *1, 2, 2, 2, 1,3, 1
1Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, 2Pediatric Cardiology Unit, Departments of Women’s and Children’s Health, University of Padua, 3Labatt Family Heart Centre, Department of Cardiovascular Surgery, The Hospital for Sick Children, University of Toronto
* These authors contributed equally

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Vi demonstrerer, hvordan man etablerer en murinmodel af lungerodimplantation i den faldende aorta for at simulere Ross-proceduren. Denne model muliggør mellemlang / langsigtet evaluering af lungeautograftombygning i en systemisk position, der repræsenterer grundlaget for udvikling af terapeutiske strategier til fremme af tilpasningen.

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