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Isolering og dyrkning av humane fettavledede stamceller med en innovativ xenogenfri metode for humanterapi

Article DOI: 10.3791/65104-v • 06:00 min • February 3rd, 2023
February 3rd, 2023 •
*1,4, *2, 2, 3, 4, 4, 1, 1
1Department of Plastic, Reconstructive and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV, 2Cell and Tissue Engineering Lab, IRCCS Ospedale Galeazzi Sant'Ambrogio, 3Unit of Regenerative Therapy, Plastic, Reconstructive and Hand Surgery, Department of Musculoskeletal Medicine, Lausanne University Hospital, 4Centre for the Cellular Microenvironment, University of Glasgow
* These authors contributed equally

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Xenogene (kjemiske eller dyreavledede) produkter introdusert i celleterapiforberedelses-/manipulasjonstrinnene er forbundet med økt risiko for immunreaktivitet og patogen overføring hos vertspasienter. Her beskrives en komplett xenogenfri metode for isolering og in vitro-ekspansjon av humane fettderiverte stamceller.

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