Peripheral Neurons
Peripheral Neurons - Related Videos
12:02
Laser Capture Microdissection of Drosophila Peripheral Neurons
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Cited by 25 •
2010
In this video-article we present a method for isolating single or multiple Drosophila da neurons from third instar larvae using the infrared capture (IR) class of Laser Capture Microdissection (LCM). RNA obtained from the isolated neurons can be readily used for downstream applications including qRT-PCR or microarray analyses.
12:04
Isolation and Purification of Drosophila Peripheral Neurons by Magnetic Bead Sorting
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Cited by 25 •
2009
In this video-article we present a method for the isolation and purification of Drosophila peripheral neurons using a fast magnetic bead assisted cell sorting strategy. RNA obtained from the isolated cells can be readily used for downstream applications including microarray analyses.
09:42
Morphological Analysis of Drosophila Larval Peripheral Sensory Neuron Dendrites and Axons Using Genetic Mosaics
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Cited by 16 •
2011
The dendritic arborization sensory neurons of the Drosophila larval peripheral nervous system are useful models to elucidate both general and neuron class-specific mechanisms of neuron differentiation. We present a practical guide to generate and analyze dendritic arborization neuron genetic mosaics.
09:17
Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration
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Cited by 35 •
2015
Dorsal root ganglia (DRG) are structures containing the sensory neurons of the peripheral nervous system. When dissociated, they can be co-cultured with SC-like adipose-derived stem cells (ASC), providing a valuable model to study in vitro nerve regeneration and myelination, mimicking the in vivo environment at the injury site.
07:51
Peripheral Venous Cannulation
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2023
Source: Sharon Bord, MD, Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA Placement of an intravenous (IV) catheter is one of the key procedures in medicine. The IV catheter allows patients to receive critical medications, including pain medicine, insulin, antibiotics, blood products, and fluids for rehydration. Additionally, placing an IV catheter allows for blood samples to be obtained, which can be sent to the laboratory for testing and...
FAQs
Schwann cells are important because they support axon function and can assist repair after injury. Their role makes them relevant to engineered strategies intended to guide or reconnect damaged axons. Designs involving nerve guidance conduits, biomaterials, or tissue-engineered grafts therefore aim to create conditions that support axonal recovery while retaining the cellular support needed for functional reconnection.
These signaling categories connect peripheral tissues with the central nervous system in different functional contexts. A bioengineered interface intended for neural repair or prosthetic technology must therefore be evaluated according to the type of connection it is meant to support. Distinguishing sensory, motor, and autonomic functions helps researchers relate axon regeneration to the desired physiological outcome.
These components address different engineering needs in neural repair. Nerve guidance conduits are used to promote directed axon regeneration, biomaterials provide engineered environments for repair strategies, and electrical interfaces support the development of prosthetic technologies. Studying them together allows researchers to examine how physical materials and signal-related interfaces may contribute to functional reconnection.
Tissue-engineered grafts provide one approach for promoting axon regeneration and reconnecting injured peripheral nerves, whereas conduits, biomaterials, and electrical interfaces represent other engineering strategies. Comparing these approaches helps researchers determine which design is most appropriate for a particular repair objective. The comparison is especially relevant when laboratory models are used to evaluate neural repair strategies before broader application.
Laboratory models allow researchers to examine whether engineered approaches support axon regeneration and functional reconnection. They can be used to study nerve guidance conduits, biomaterials, electrical interfaces, and tissue-engineered grafts within a controlled research setting. These models provide a way to compare repair strategies and investigate their relevance to peripheral nerve damage and prosthetic technology development.
They are particularly relevant when researchers need to address peripheral nerve damage, develop prosthetic technologies, or create laboratory systems for testing neural repair. Their study connects biological questions about axon regeneration and Schwann cell support with engineering goals such as guided growth, engineered graft design, and functional reconnection between peripheral tissues and the central nervous system.